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Development of a Non-invasive Assessment of Human Bone Quality Using Spatially Offset Raman Spectroscopy

NCT02814591 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 245

Last updated 2022-11-23

No results posted yet for this study

Summary

In this study spatially offset Raman spectroscopy (SORS), which allows the collection of Raman spectra through turbid media, is being applied to collect Raman spectra of bone. The principal aim to find ways to use Raman spectroscopy to assess bone quality in vivo.

Conditions

Interventions

DEVICE

spatially offset Raman spectrometer (SORS)

Raman spectra will be collected non-invasively from patients using a lower power 830 nm laser. A probe is brought into gentle contact with the patients skin and measurements taken. The laser power has a pre-defined safe threshold of 30 mW into a 3.5 mm diameter aperture. Built in device safety features prevent this threshold from being exceeded. The probe that comes into patient contact is suitable for disinfecting.

Sponsors & Collaborators

  • Royal National Orthopaedic Hospital NHS Trust

    collaborator OTHER

  • Science & Technology Facilities Council

    collaborator UNKNOWN

  • University College, London

    lead OTHER

Principal Investigators

  • Helen Birch, Professor · UCL

  • Panos Gikas, Consultant Rheumatologist · Royal National Orthopaedic Hospital NHS Trust (RNOH)

Eligibility

Min Age
0 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-10-31
Primary Completion
2024-06-30
Completion
2025-06-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02814591 on ClinicalTrials.gov