Exercise as an Modulator of Immunological Risk Factors for Osteoporosis
NCT02765945 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 43
Last updated 2016-05-09
Summary
This is the second phase of a study designed to determine the immunological effects of long-term exercise on risk factors for ischemic heart disease (phase 1) and osteoporosis (phase 2). The results indicate that six months of moderate intensity exercise reduces bone resorption and increases the secretion of anti-osteoclastogenic cytokines by peripheral blood mononuclear cells.
Conditions
Interventions
- OTHER
-
Supervised exercise program
Subjects were enrolled in a hospital-based wellness center where, after analysis of their medical history and previous levels of physical activity ands documentation of a normal exercise stress test, they chose individually tailored exercise programs
Sponsors & Collaborators
-
East Tennessee State University
lead OTHER
Principal Investigators
-
John K Smith, MD · James H. Quillen College of Medicine, Johnson City, Tennesse, United States 70571
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 30 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 1996-12-31
- Primary Completion
- 1998-04-30
- Completion
- 1998-04-30
Countries
- United States
Study Locations
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