Exercise as an Modulator of Immunological Risk Factors for Osteoporosis

NCT02765945 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 43

Last updated 2016-05-09

No results posted yet for this study

Summary

This is the second phase of a study designed to determine the immunological effects of long-term exercise on risk factors for ischemic heart disease (phase 1) and osteoporosis (phase 2). The results indicate that six months of moderate intensity exercise reduces bone resorption and increases the secretion of anti-osteoclastogenic cytokines by peripheral blood mononuclear cells.

Conditions

Interventions

OTHER

Supervised exercise program

Subjects were enrolled in a hospital-based wellness center where, after analysis of their medical history and previous levels of physical activity ands documentation of a normal exercise stress test, they chose individually tailored exercise programs

Sponsors & Collaborators

  • East Tennessee State University

    lead OTHER

Principal Investigators

  • John K Smith, MD · James H. Quillen College of Medicine, Johnson City, Tennesse, United States 70571

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
30 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
1996-12-31
Primary Completion
1998-04-30
Completion
1998-04-30

Countries

  • United States

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02765945 on ClinicalTrials.gov