Heart Rate Reducing Therapy in Cardiac CT Using Ivabradine and Bisoprolol
NCT02764970 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 112
Last updated 2018-03-19
Summary
Out-patients scheduled for coronary computer tomographic angiography (CCTA) were screened regarding their baseline heart rate. If heart rate was \> 75, patients were pretreated with 10mg bisoprolol (group 1) or 10mg bisoprolol plus 7.5mg ivabradine (group 2) to reduce heart rate one our before CCTA was performed.
Heart rate, additional use of i.v. bradycardic agents, motion artefacts, radiation dose and drug tolerance was monitored.
Conditions
- Bradycardia
Interventions
- DRUG
-
Ivabradine 7.5mg orally
additive use to the standard medication with bisoprolol
Sponsors & Collaborators
-
Medical University of Graz
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2015-02-28
- Primary Completion
- 2015-09-30
- Completion
- 2016-01-31
More Related Trials
-
The Influence of Heart Rate Reduction Upon Central Arterial Pressure in Younger and Older Healthy Individuals
NCT01029223 ·Status: WITHDRAWN ·Phase: PHASE4
-
To Assess the Anti-anginal Safety and Efficacy of Ivabradine in Subjects With Stable,Symptomatic Chronic Angina
NCT02623569 ·Status: UNKNOWN ·Phase: PHASE2
-
Ivabradine Versus Beta-blockers in the Treatment of Inappropriate Sinus Tachycardia
NCT01657136 ·Status: COMPLETED ·Phase: PHASE3
-
Ivabradine to Improve Endothelial Function in Patients With Coronary Artery Disease
NCT02681978 ·Status: COMPLETED ·Phase: PHASE4
-
Promotion of Coronary Collateral Function by Ivabradine-Induced Bradycardia in Patients With Coronary Artery Disease
NCT01039389 ·Status: COMPLETED ·Phase: NA
-
Effects of Heart Rate Reduction on Central Arterial Pressure in Healthy Individuals
NCT00825123 ·Status: TERMINATED ·Phase: PHASE4
-
Effect of Ivabradine on Heart Rate & Effort Tolerance in Mitral Stenosis in Sinus Rhythm
NCT01022463 ·Status: COMPLETED ·Phase: PHASE3
-
Pharmacokinetic Drug-Drug Interaction Between Bisoprolol and Ivabradine in Healthy Volunteers
NCT03485482 ·Status: COMPLETED ·Phase: PHASE3
-
Study to Investigate the Effect of Heart Rate Reduction With Ivabradine on Vascular Elastic Properties and Endothelial Function in Patients With Stable Coronary Heart Disease
NCT01768585 ·Status: UNKNOWN ·Phase: PHASE4
-
Iatrogenic Chronotropic Incompetence and Exercise Tolerance in Heart Failure
NCT02086422 ·Status: UNKNOWN ·Phase: NA
-
Efficacy and Safety of Ivabradine on Top of Atenolol in Stable Angina Pectoris
NCT00202566 ·Status: COMPLETED ·Phase: PHASE3
-
Bisoprolol in Hypertension: Effect on Concomitant Elevated Heart Rate
NCT01109043 ·Status: COMPLETED
-
PeRiOperaTivE CardioproTection With Ivabradine in Non-cardiac Surgery
NCT04436016 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy of Oral Ivabradine in Patients Presenting With NSTEMI
NCT04285736 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Beta-blockers in i-PAH
NCT01246037 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Effect of Pharmacological Heart Rate Reduction on Visco-elastic Properties of the Arterial Wall (BRADYVASC)
NCT02584439 ·Status: COMPLETED ·Phase: PHASE3
-
The Impact of Heart Rate on Central Blood Pressure in Sick Sinus Syndrome Patients With a Permanent Cardiac Pacemaker
NCT03245996 ·Status: COMPLETED ·Phase: PHASE4
-
Ivabradine in Patients With Congestive Heart Failure
NCT04448899 ·Status: COMPLETED ·Phase: PHASE4
-
Role of Ivabradine for Heart Rate Control in Management of Patients With Sepsis and Septic Shock
NCT06742164 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
pErsonalised Nocebo Assessment of Beta-blockEr Symptoms in Heart Failure
NCT07029906 ·Status: RECRUITING ·Phase: NA
-
Ivabradine in Cirrhotic Cardiomyopathy
NCT04111133 ·Status: RECRUITING ·Phase: NA
-
Acute Dietary Nitrate in Dilated Cardiomyopathy
NCT02471417 ·Status: COMPLETED ·Phase: NA
-
Hostility Reduction Program to Improve Autonomic Regulation of the Heart
NCT00365196 ·Status: COMPLETED ·Phase: NA
-
Treating Intraoperative Bradycardia in Non-cardiac Surgery Patients With Atropine at Heart Rates Below 60 Versus 30 Beats Per Minute and Norepinephrine Requirements
NCT06922097 ·Status: COMPLETED ·Phase: NA
-
A Study to Evaluate the Effect of MCI-186 at Therapeutic and Supra-Therapeutic Doses on the QT Interval(QT)/Corrected QT Interval(QTc) Interval in Healthy Subjects
NCT04029090 ·Status: COMPLETED ·Phase: PHASE1