fMRI Guided TMS Enhancement of Associative Memory Networks
NCT02749422 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 8
Last updated 2024-05-29
Summary
This is a randomized, single-blinded, controlled phase 1 study to demonstrate feasibility and explore the neurophysiologic and clinical effects of repetitive transcranial magnetic stimulation (TMS) interventions in epilepsy patients and healthy controls. The inclusion of a control group will be used to see whether epilepsy patients, who suffer from a higher degree of comorbid memory difficulty presumably from entorhinal-hippocampal dysfunction, can benefit from a TMS intervention can benefit as much as a healthy matched population. Investigators will also be looking at functional connectivity between the hippocampus and cortical regions
Conditions
Interventions
- DIAGNOSTIC_TEST
-
MagStim RapidStim2
Repetitive transcranial magnetic stimulation (TMS)
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Anli Liu, MD · New York University Medical School
Study Design
- Allocation
- RANDOMIZED
- Purpose
- SUPPORTIVE_CARE
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2016-10-14
- Primary Completion
- 2023-03-30
- Completion
- 2023-03-30
- FDA Device
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Transcranial Magnetic Stimulation and Anti-epileptic Effect: Optimization and Evaluation With Electrophysiology.
NCT00382707 ·Status: TERMINATED ·Phase: NA
-
TMS for Investigating Memory Facilitation
NCT05462782 ·Status: TERMINATED ·Phase: NA
-
Task-dependent Effects of TMS on the Neural Biomarkers of Episodic Memory
NCT04694131 ·Status: COMPLETED ·Phase: NA
-
Modulating the Hippocampal and Striatal Memory Networks With rTMS
NCT03994120 ·Status: COMPLETED ·Phase: NA
-
fMRI-neuronavigated rTMS for the Treatment of Major Depression Associated With TBI
NCT02980484 ·Status: TERMINATED ·Phase: PHASE2
-
Targeted Transcranial Magnetic Stimulation to Improve Hippocampal-dependent Declarative Memory Abilities
NCT03574207 ·Status: RECRUITING ·Phase: NA
-
Functional Connectivity as a Biomarker of rTMS
NCT03050801 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Transmagnetic Stimulation Pilot in Early Stage Alzheimer's Disease
NCT05292222 ·Status: COMPLETED ·Phase: NA
-
Efficacy of Repetitive Transcranial Magnetic Stimulation for Improvement of Memory in Older Adults With TBI
NCT03727737 ·Status: COMPLETED ·Phase: NA
-
The Effect of Repetitive Transcranial Magnetic Stimulation on Brain Activity in Healthy Human Volunteers
NCT01369264 ·Status: COMPLETED ·Phase: NA
-
Network-guided TMS in Early Alzheimer's Disease
NCT04549155 ·Status: COMPLETED ·Phase: NA
-
TMS With Real-time E-field and EEG Source Imaging
NCT06645613 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Network Control TMS fMRI
NCT05736458 ·Status: TERMINATED ·Phase: NA
-
Low Frequency TMS for Depression in Epilepsy
NCT03105700 ·Status: COMPLETED ·Phase: NA
-
Transcranial Magnetic Stimulation to Treat Epilepsy
NCT00048490 ·Status: COMPLETED ·Phase: PHASE2
-
Transcranial Magnetic Stimulation for Epilepsy
NCT02757547 ·Status: TERMINATED ·Phase: NA
-
TMS in Preclinical and Prodromal AD: Modulation of Brain Networks and Memory
NCT04294888 ·Status: TERMINATED ·Phase: NA
-
Supporting Episodic Memory With Transcranial Direct Current Stimulation in Healthy Controls and Dementia Patients
NCT03227185 ·Status: TERMINATED ·Phase: NA
-
A Pilot Clinical Trial Study to Determine the Safety of the Application of a Wearable Medical Electromagnetic Generator
NCT06543797 ·Status: NOT_YET_RECRUITING ·Phase: EARLY_PHASE1
-
Concurrent fMRI-guided rTMS and Cognitive Therapy for the Treatment of Major Depressive Episodes
NCT03289923 ·Status: COMPLETED ·Phase: NA
-
Effects of rTMS on Human Brain Activity
NCT04242810 ·Status: WITHDRAWN ·Phase: NA
-
High-Definition Transcranial Direct Current Stimulation (HD-tDCS) for Sensory Deficits in Complex Traumatic Brain Injury
NCT03799458 ·Status: COMPLETED ·Phase: NA
-
Repetitive Transcranial Magnetic Stimulation for Dementia
NCT02621424 ·Status: COMPLETED ·Phase: NA
-
Mini Theta Burst TMS in MDD Patients
NCT04014959 ·Status: COMPLETED ·Phase: NA
-
Effect of Transcranial Magnetic Stimulation to the Frontoparietal Attention Network on Anxiety Potentiated Startle
NCT03027414 ·Status: COMPLETED ·Phase: NA