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Frameless Stereotactic Radiosurgery for Intact Brain Metastases

NCT02747303 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 166

Last updated 2025-12-29

No results posted yet for this study

Summary

This is a randomized study to determine if not treating planning target volume (PTV) margins during radiation therapy worsens progression free survival rates in patients with brain metastases.

Conditions

Interventions

PROCEDURE

Stereotactic Radiosurgery

The SRS dose will depend on the maximum diameter of the gross tumor volume (GTV)

Sponsors & Collaborators

  • University of Chicago

    lead OTHER

Principal Investigators

  • Steven J. Chmura, M.D., Ph.D. · University of Chicago

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-09-05
Primary Completion
2028-08-22
Completion
2028-08-22

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02747303 on ClinicalTrials.gov