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Transcription Factor Runx2 in Necrotic Femoral Head Tissue

NCT02735538 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2016-04-13

No results posted yet for this study

Summary

The trial detected mRNA expression of several bone repair-related genes, including Runx2, in the femoral head and neck of patients with osteonecrosis of femoral head (ONFH) . Runx2 expression was compared with that of identical tissue from osteoarthritis patients to identify expression in necrotic femoral head tissue, which will help clarify the role and possible clinical significance of Runx2 in femoral head necrosis, bone repair and reconstruction.

Conditions

  • Osteonecrosis of Femoral Head

Interventions

PROCEDURE

osteonecrosis of femoral head group

The patients with osteonecrosis of femoral head will undergo total hip replacement.

PROCEDURE

osteoarthritis group

The patients with osteoarthritis will undergo total hip replacement.

Sponsors & Collaborators

  • Shengjing Hospital

    lead OTHER

Principal Investigators

  • Liqing Yang, M.D. · Shengjing Hospital of China Medical University, China

Eligibility

Min Age
25 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-07-31
Primary Completion
2010-06-30
Completion
2011-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02735538 on ClinicalTrials.gov