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Addressing Motion and Confounds Issues in Resting fMRI- Application of Multi-echo EPI Scanning

NCT02720562 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 80

Last updated 2016-03-28

No results posted yet for this study

Summary

Resting state functional MRI is widely used for studying brain functional networks. However, in-scanner head movement and other non-neuronal noise can disproportionately bias connectivity estimates, despite various preprocessing efforts. To address these issues, the technique combining data acquisition with multiecho (ME) echo planar imaging and analysis with spatial independent component analysis (ICA), called ME-ICA, has been develop to distinguish BOLD (neuronal) and non-BOLD (artifactual) components based on linear echo-time dependence of signals, and has been demonstrated to successfully remove non-neuronal confounds. Nonetheless, such research approach has never been applied in psychiatric populations. The study aims to fill in the gap as shown in the following.

Conditions

  • Attention-deficit/Hyperactivity Disorder

Sponsors & Collaborators

  • National Taiwan University Hospital

    lead OTHER

Principal Investigators

  • Hsiang-Yuan Lin, MD · Dept of Psychiatry, National Taiwan University Hospital

  • Susan Shur-Fen Gau, MD, PhD · National Taiwan University Hospital & College of Medicine

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-01-31
Primary Completion
2015-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02720562 on ClinicalTrials.gov