The Influence of ABCB1、CYP3A4、CYP3A5、POR Genetic Polymorphism and Other Factors on Tacrolimus Blood Concentration
NCT02707822 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 440
Last updated 2016-03-14
Summary
The purpose of the study is to identify factors that may influence tacrolimus (TAC) pharmacokinetics, and the impact of gene polymorphism (ABCB1, CYP3A4, CYP3A5, POR) on pharmacokinetics of TAC in Taiwanese.
Conditions
- Kidney Transplantation
- Liver Transplantation
Interventions
- OTHER
-
Clinical and genetic factors
Sponsors & Collaborators
-
National Taiwan University Hospital
lead OTHER
Principal Investigators
-
Meng-Kun Tsai · National Taiwan University Hospital
Eligibility
- Min Age
- 20 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-01-31
- Primary Completion
- 2018-12-31
- Completion
- 2018-12-31
Countries
- Taiwan
Study Locations
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