Study Evaluating the Interest of Vismodegib as Neo-adjuvant Treatment of Basal Cell Carcinoma (BCC)
NCT02667574 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 55
Last updated 2026-04-22
Summary
Open-label, non-comparative, multicenter, phase II study of Vismodegib in patients with locally advanced BCC.
Conditions
Interventions
- DRUG
-
ERIVEDGE
Sponsors & Collaborators
- collaborator INDUSTRY
-
University Hospital, Lille
lead OTHER
Principal Investigators
-
Laurent MORTIER, MD,PhD · University Hospital, Lille
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-11-18
- Primary Completion
- 2020-07-15
- Completion
- 2020-07-15
Countries
- France
Study Locations
More Related Trials
-
To Assess The Efficacy And Safety Of Vismodegib And Radiotherapy In Advanced Basal Cell Carcinoma
NCT02956889 ·Status: TERMINATED ·Phase: PHASE2
-
Oral Hedgehog Inhibitors in the Treatment of Basal Cell Carcinoma in the Netherlands: a Prospective Registration Study
NCT05463757 ·Status: RECRUITING
-
Mohs Versus Traditional Surgery - Basal-Cell Carcinomas (BCC)
NCT00699829 ·Status: UNKNOWN
-
Post-market Multi-Center RETRO-Prospective Study to Assess Long-term Clinical Outcomes NMSC Patients Treated With eBx
NCT05257486 ·Status: COMPLETED
-
Safety and Efficacy Study of a New Chemotherapy Agent to Treat Metastatic Melanoma
NCT00185302 ·Status: COMPLETED ·Phase: PHASE2
-
A Prospective Non-Interventional Study in Participants Receiving Nivolumab in Adjuvant Setting for Resected Melanoma in Real-World Conditions in France
NCT04550247 ·Status: ACTIVE_NOT_RECRUITING
-
L19IL2/TNF in Patients With Basal Cell Carcinoma
NCT07227870 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Pembrolizumab With or Without Vismodegib in Treating Metastatic or Unresectable Basal Cell Skin Cancer
NCT02690948 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
An Extension Protocol for the Extended Use of Talimogene Laherparepvec for Eligible Patients Who Participated in Study 002/03 (NCT00289016)
NCT02574260 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate Safety and Therapeutic Activity of RO6874281 in Combination with Pembrolizumab, in Participants with Advanced or Metastatic Melanoma
NCT03875079 ·Status: COMPLETED ·Phase: PHASE1
-
Cabozantinib in Recurrent/Metastatic Merkel Cell Carcinoma
NCT02036476 ·Status: TERMINATED ·Phase: PHASE2
-
Reflectance Confocal Microscopy to Diagnose BCC
NCT03509415 ·Status: COMPLETED
-
Outcome Research of a European Registry Platform on Real-world Treatment Data of Patients with Advanced NMSC
NCT05741073 ·Status: RECRUITING
-
mRNA Electroporated Autologous Dendritic Cells for Stage III/IV Melanoma
NCT01676779 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy of Bevacizumab Monotherapy in Treatment of Metastatic Melanoma
NCT00139360 ·Status: COMPLETED ·Phase: PHASE2
-
Post-occlusive Reactive Hyperemia and Basal-cell Carcinoma
NCT01455363 ·Status: COMPLETED ·Phase: NA
-
Effectiveness, Safety and Use of Nivolumab Administered During the French Temporary Authorization for Use in Patients With Advanced Melanoma
NCT03504696 ·Status: COMPLETED
-
The VIDYA Study-designed to Determine if Patients With a History of Basal Cell Carcinoma Are More Inclined to Return for Follow-up if Their Risk of a Subsequent Basal Cell Carcinoma is Quantitated.
NCT04093401 ·Status: WITHDRAWN ·Phase: NA
-
Immunotherapy +/- EGFR Inhibitor In Advanced/Metastatic cSCC: Tackling Primary And Secondary Resistance
NCT03666325 ·Status: UNKNOWN ·Phase: PHASE2
-
Study of Pembrolizumab (MK-3475) in Adults With Recurrent/Metastatic Cutaneous Squamous Cell Carcinoma (cSCC) or Locally Advanced Unresectable cSCC (MK-3475-629/KEYNOTE-629)
NCT03284424 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase 1b Study of the Selective HDAC Inhibitor Mocetinostat in Combination With Ipilimumab and Nivolumab in Patients With Unresectable Stage III or Stage IV Melanoma
NCT03565406 ·Status: TERMINATED ·Phase: PHASE1
-
Comparison of eBX and Mohs Surgery for Treatment of Early-stage Non-melanoma Skin Cancer a Matched Pair Cohort Study.
NCT03024866 ·Status: COMPLETED
-
Study Evaluating the Efficacy and Safety of 0.05% Ingenol Mebutate (Picato® 500) in the Treatment of Basal Cell Carcinoma
NCT03546166 ·Status: COMPLETED ·Phase: PHASE2
-
Neoadjuvant Chemotherapy and Retifanlimab in Patients With Selected Sarcomas (TORNADO)
NCT04968106 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study of Talimogene Laherparepvec in Stage IIIc and Stage IV Malignant Melanoma
NCT00289016 ·Status: COMPLETED ·Phase: PHASE2