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Hemostasis Alterations in Neurosurgical Patients

NCT02652897 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 120

Last updated 2018-11-27

No results posted yet for this study

Summary

Prospective, observational study aimed to investigate the specific hemostatic alterations in patients undergoing glial tumor resection.

Conditions

  • Glioma
  • Coagulopathy
  • Acquired Platelet Function Disorder
  • Thromboelastometry
  • Surgery

Interventions

PROCEDURE

Exposure to glioma resection surgery

The following blood samples will be drawn for hemostasis evaluation: 1. Conventional clotting tests, 2. Rotational thromboelastometry (ROTEM), including EXTEM and FIBTEM; 3. Platelet function as assessed by PFA-200 for; and 4. Platelet function as assessed by ara-tem, adp-tem and trap-tem. All the analyses will be performed before (within a period 24-h before surgery) and after (within of the following periods: 2 h, 24 h and 48 h after surgery).

PROCEDURE

Exposure to colon resection surgery

The following blood samples will be drawn for hemostasis evaluation: 1. Conventional clotting tests, 2. Rotational thromboelastometry (ROTEM), including EXTEM and FIBTEM; 3. Platelet function as assessed by PFA-200 for; and 4. Platelet function as assessed by ara-tem, adp-tem and trap-tem. All the analyses will be performed before (within a period 24-h before surgery) and after (within of the following periods: 2 h, 24 h and 48 h after surgery).

Sponsors & Collaborators

  • Instituto de Salud Carlos III

    collaborator OTHER_GOV

  • Santiago R. Leal-Noval

    lead OTHER

Principal Investigators

  • Santiago R. Leal-Noval, MD Ph.D · University Hospital "Virgen del Rocío", Seville, Spain

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-05-31
Primary Completion
2019-02-28
Completion
2019-03-31

Countries

  • Spain

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02652897 on ClinicalTrials.gov