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Saliva Cortisol Measurement as a Screening Test for Suspicious Cushings Syndrome in Children.

NCT02646553 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 70

Last updated 2017-08-16

No results posted yet for this study

Summary

Cortisol overproduction ( Cushings syndrome) is a condition where the patient have a special fat distribution, with accumulation of fat around the abdomen and in the neck, with thinner limbs and weak musculature. The condition can be difficult to separate from adipositas in general. Screening for hypercortisolism in adults has been easier the last years, because we can measure free cortisol in saliva samples at late night. In children we still dont have reference ranges for saliva cortisol in children, so the screening is still troublesome, based on Collection of 24-hour urine.The meaning of this study is to establish reference ranges for saliva cortisol, and evaluate in a cohort with adipose children if screening with saliva cortisol is sensitive and specific enough to be the New screening test for hypercortisolism in children too.

Conditions

  • Cushings Syndrome

Interventions

OTHER

Children refered to the obesity clinic

Compere if urine cortisol is as good as saliva cortisol as a screening for hypercortisolism in children.

Sponsors & Collaborators

  • Haukeland University Hospital

    lead OTHER

Principal Investigators

  • Grethe Åstrøm Ueland, MD · Haukeland University Hospital

Eligibility

Min Age
4 Years
Max Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-05-31
Primary Completion
2019-04-30
Completion
2019-04-30

Countries

  • Norway

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02646553 on ClinicalTrials.gov