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Circulating BDNF in Patients With Atrial Fibrillation Undergoing Catheter Ablation or Exercise Training

NCT02627183 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2026-05-01

No results posted yet for this study

Summary

The main purpose of this project is to determine the impact of atrial fibrillation interventions (catheter ablation and exercise training) on circulating BDNF concentrations in patients with atrial fibrillation. It also seeks to determine if there is a relation between circulating BDNF concentrations and mental health (depression severity, quality of life and symptoms) among those undergoing interventions for atrial fibrillation catheter ablation or exercise training.

Conditions

Interventions

PROCEDURE

Catheter ablation

Subjects undergoing catheter ablation for the first time for atrial fibrillation as part of their regular care (regardless of involvement in this study).

BEHAVIORAL

Exercise training

Subjects participating in supervised exercise classes for up to 60 minutes in length 2 times/week as part of their involvement in another study (NCT02602457).

Sponsors & Collaborators

  • Ottawa Heart Institute Research Corporation

    lead OTHER

Principal Investigators

  • Jennifer L Reed, PhD · Ottawa Heart Institute Research Corporation

  • Girish Nair, MD · Ottawa Heart Institute Research Corporation

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-02-16
Primary Completion
2024-06-13
Completion
2024-06-13

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02627183 on ClinicalTrials.gov