Ibrutinib in Relapsed Nodular Lymphocyte-predominant Hodgkin Lymphoma (NLPHL)
NCT02626884 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 14
Last updated 2021-04-08
Summary
The purpose of this trial is to determine
1. Disease stabilization/response rate after six 21-day cycles of ibrutinib
2. Remission status after six, twelve and 20 21-day cycles of ibrutinib
Conditions
- Nodular Lymphocyte-Predominant Hodgkin's Lymphoma
Interventions
- DRUG
Sponsors & Collaborators
-
University of Cologne
lead OTHER
Principal Investigators
-
Andreas Engert, Prof. · University Hospital of Cologne
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 99 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-08-31
- Primary Completion
- 2020-08-31
- Completion
- 2020-08-31
Countries
- Germany
Study Locations
More Related Trials
-
Ibrutinib in Treating Patients With Relapsed or Refractory Follicular Lymphoma
NCT01849263 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Lenalidomide and Ibrutinib in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma
NCT01955499 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Ibrutinib in Treating Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma in Patients With HIV Infection
NCT02109224 ·Status: TERMINATED ·Phase: PHASE1
-
Ipilimumab With or Without Nivolumab in Relapsed/Refractory cHL
NCT04938232 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Pembrolizumab in Combination With Salvage Chemotherapy for First-relapsed or Refractory Classical Hodgkin Lymphoma
NCT04838652 ·Status: RECRUITING ·Phase: PHASE2
-
Pembrolizumab Alone or With Idelalisib or Ibrutinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Other Low-Grade B-Cell Non-Hodgkin Lymphomas
NCT02332980 ·Status: COMPLETED ·Phase: PHASE2
-
Ibrutinib in Treating Patients With Relapsed or Refractory Transformed Indolent B-cell Non-Hodgkin Lymphoma
NCT02207062 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Nivolumab in Patients With Classical Hodgkin's Lymphoma (Registrational)
NCT02181738 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Nivolumab in Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Relapsed/Refractory Primary Testicular Lymphoma (PTL)
NCT02857426 ·Status: COMPLETED ·Phase: PHASE2
-
Ibrutinib in Treating Patients With Refractory or Relapsed Lymphoma After Donor Stem Cell Transplant
NCT02869633 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluating Combination of Nivolumab and Axatilimab in Patients With Relapsed/Refractory Classical Hodgkin Lymphoma
NCT05723055 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Pembrolizumab in First-Line Treatment of Advanced-Stage Classical Hodgkin Lymphoma
NCT06045195 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Nivolumab Maintenance Therapy After Autologous Stem Cell Transplant in Hodgkin Lymphoma Pts at Relapse/Progression Risk
NCT03436862 ·Status: COMPLETED ·Phase: PHASE2
-
Phase1/2 Study of IPH6501 in Patients With Relapsed /Refractory B-Cell Non-Hodgkin Lymphoma
NCT06088654 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Ofatumumab in Nodular Lymphocyte Predominant Hodgkin Lymphoma (NLPHL)
NCT01187303 ·Status: COMPLETED ·Phase: PHASE2
-
Ibrutinib or Idelalisib in Treating Patients With Persistent or Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Non-Hodgkin Lymphoma After Donor Stem Cell Transplant
NCT02662296 ·Status: WITHDRAWN ·Phase: PHASE2
-
Lenalidomide and Blinatumomab for the Treatment of Relapsed Non-Hodgkin Lymphoma
NCT02568553 ·Status: COMPLETED ·Phase: PHASE1
-
Abscopal Effect of Radiotherapy and Nivolumab in Relapsed Hodgkin Lymphoma After Anti-PD1 Therapy
NCT03480334 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Study of Atezolizumab in Relapsed or Refractory Hodgkin Lymphoma
NCT03120676 ·Status: TERMINATED ·Phase: PHASE2
-
Ibrutinib and Palbociclib in Treating Patients With Previously Treated Mantle Cell Lymphoma
NCT02159755 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Study of Epcoritamab and Ibrutinib in People With Central Nervous System Lymphoma (CNSL)
NCT07082868 ·Status: RECRUITING ·Phase: PHASE1
-
Ibrutinib and Brentuximab Vedotin in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma
NCT02744612 ·Status: COMPLETED ·Phase: PHASE2
-
Nivolumab With Ruxolitinib in Relapsed or Refractory Classical Hodgkin Lymphoma
NCT03681561 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
TGR-1202 and Ibrutinib in Treating Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
NCT02874404 ·Status: COMPLETED ·Phase: PHASE2
-
BI 836826 Dose Escalation in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma (NHL)
NCT01403948 ·Status: COMPLETED ·Phase: PHASE1