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Repigmentation Patterns Induced by NB-UVB and Their Relationship With Melanocytic Migration in Vitiligo

NCT02625012 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2015-12-09

No results posted yet for this study

Summary

Vitiligo is the most common acquired depigmented disorder of the skin characterized by destruction of melanocytes resulting in well-circumscribed achromic macules. Ultraviolet phototherapy with narrow band (UVB-NB) is currently one of the treatments of choice, because it is able to induce proliferation, differentiation, maturation and migration of melanocytes. This repigmentation has distinctive patterns such as follicular, marginal, and diffuse. The aim of this study is to observe the dynamics of migration and proliferation, in vitiligo patients under UVB radiation phototherapy treatment. The investigators will evaluate this process by measuring FAK (focal adhesion kinase ) and c-Kit by immunohistochemistry and reverse transcriptase polymerase chain reaction assay.

Conditions

  • Vitiligo

Sponsors & Collaborators

  • Hospital Central "Dr. Ignacio Morones Prieto"

    collaborator OTHER

  • Juan Pablo Castanedo-Cazares

    lead OTHER

Principal Investigators

  • Diego Cortes-Garcia, PhD · Universidad Autonoma de San Luis Potosi

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-01-31
Primary Completion
2016-01-31
Completion
2016-04-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02625012 on ClinicalTrials.gov