Proton Pump Inhibitors Use in Patients With Psoriasis
NCT02624544 · Status: WITHDRAWN · Phase: PHASE4 · Type: INTERVENTIONAL
Last updated 2022-08-05
Summary
Proton pump inhibitors act in blocking acid secretion and also have antioxidant and anti-inflammatory properties. For that mechanisms possibly PPIs may have an anti-inflammatory action with improvement in skin lesions in patients with psoriasis.
Conditions
Interventions
- DRUG
-
esomeprazole
esomex 40 mg twice daily
- DRUG
-
desonide
topical corticosteroid desonid 0,1% b.i.d
Sponsors & Collaborators
-
EMS
lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-01-31
- Primary Completion
- 2016-01-31
- Completion
- 2016-12-31
More Related Trials
-
PPI-Rebound-Trial. A Study of the Clinical Relevance of the Acid Rebound Phenomena
NCT00526006 ·Status: UNKNOWN ·Phase: PHASE4
-
PPI And Food Effect Study For PF-06463922 In Healthy Volunteers
NCT02569554 ·Status: COMPLETED ·Phase: PHASE1
-
Proton Pump Inhibitor (PPI, Rabeprazole) Effect On Tablet Formulation Of Palbociclib
NCT03220191 ·Status: COMPLETED ·Phase: PHASE1
-
Does Intensive Acid Suppression Reduce Esophageal Inflammation and Recurrent Barrett's Esophagus Following Ablation?
NCT01093755 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Evaluate the Effects of Food and Esomeprazole on the Pharmacokinetics of Crizotinib in a Coated Microsphere Formulation.
NCT03137134 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy of Dexlansoprazole MR on Heartburn Control in Participants Previously Receiving Twice Daily Proton Pump Inhibitor Therapy
NCT00847808 ·Status: COMPLETED ·Phase: PHASE3
-
Role of Pain Modulation in GERD Patients Who Failed Standard Dose PPI
NCT00539240 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Averting Complications of Proton Pump Inhibitor Therapy by Effervescent Calcium Magnesium Citrate
NCT03812380 ·Status: TERMINATED ·Phase: PHASE3
-
Pilot Study To Investigate The Association Between Acid Control And Heartburn Symptoms After Proton Pump Inhibitor Treatment
NCT02708355 ·Status: COMPLETED ·Phase: PHASE4
-
Comparing Clinical Efficacy of One-Week Dual Delayed-Release Dexlansoprazole and Esomeprazole for GERD Grade A and B
NCT03128736 ·Status: COMPLETED ·Phase: PHASE4
-
Role of Pain Modulation in GERD Patients Who Failed Standard Dose Proton Pump Inhibitors (PPI)
NCT00251732 ·Status: COMPLETED ·Phase: PHASE4
-
Preventing Recurrent Ulcer Bleeding in Arthritis Patients Using Esomeprazole Plus Celecoxib
NCT00365313 ·Status: COMPLETED ·Phase: PHASE3
-
HMPL-523 Food Effect and Proton Pump Inhibitor Study
NCT05571787 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of Proton Pump Inhibitors on Gut Microbiota and Systemic Inflammation in Older Adults
NCT02844621 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
A Randomized, Open-Label, Comparative 3-Way Treatment Crossover Study of 24-Hour Intragastric pH Profile of Once Daily Oral Administration of Esomeprazole 40mg, Lansoprazole 30mg, and Pantoprazole 40mg at Steady State in NSAID-Using Patients
NCT00625274 ·Status: COMPLETED ·Phase: PHASE4
-
EffCaMgCit to Prevent Mineral Metabolism and Renal Complications of Chronic PPI Therapy
NCT05998863 ·Status: RECRUITING ·Phase: PHASE3
-
Proton Pump Inhibitors Effects on Dyspepsia During Ramadan Fasting
NCT05287633 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
BRAVO Study for Functional Dyspepsia
NCT01349413 ·Status: COMPLETED ·Phase: PHASE4
-
The Utility of Nexium in Chronic Cough and Reflux Disease
NCT00287339 ·Status: COMPLETED ·Phase: PHASE4
-
Gastric Functions & Proton Pump Inhibitor( PPI) Study
NCT00951431 ·Status: COMPLETED ·Phase: PHASE4
-
Oral Versus IV Proton Pump Inhibitor in High-risk Bleeding Peptic Ulcers After Endoscopic Hemostasis
NCT01182597 ·Status: UNKNOWN ·Phase: PHASE3
-
Long-term Oral Esomeprazole for Prevention of Peptic Ulcer Rebleeding in High-risk Patients
NCT02456012 ·Status: COMPLETED ·Phase: PHASE4
-
The Clinical Significance of Acid Rebound in Functional Dyspepsia
NCT01373970 ·Status: TERMINATED ·Phase: PHASE4
-
Inhibition of Gastric Acid is the Key to Satisfactory Relief of Symptoms With Esomeprazole in NUD Patients
NCT00222131 ·Status: COMPLETED ·Phase: PHASE2
-
The Role of CYP2C19 on the Eradication of H. Pylori Infection:Implication of PK/PD Relationships
NCT00162877 ·Status: UNKNOWN ·Phase: NA