The Role of CYP2C19 on the Eradication of H. Pylori Infection:Implication of PK/PD Relationships
NCT00162877 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80
Last updated 2005-11-23
Summary
The objective of this trial is to find the rationale and the optimal dose and duration of regimen for the eradication of H. pylori infection using different proton pump inhibitors.
Conditions
- Peptic Ulcer With H. Pylori Infection
- Gastritis With H. Pylori Infection
Interventions
- DRUG
-
Rabeprazole vs. Esomeprazole
Sponsors & Collaborators
-
National Taiwan University Hospital
lead OTHER
Principal Investigators
-
Jyh-Chin Yang, M.D. · Department of Internal Medicine, National Taiwan University Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-06-30
- Completion
- 2005-04-30
Countries
- Taiwan
Study Locations
More Related Trials
-
Comparison of Dexlansoprazole-based Triple and Rabeprazole-based Triple Therapies for Helicobacter Pylori Infection
NCT02541786 ·Status: COMPLETED ·Phase: PHASE4
-
The Safety and Tolerability, Pharmacokinetics of TNP-2092 Capsules in Combination With Rabeprazole Sodium Enteric-coated Tablets
NCT06337604 ·Status: COMPLETED ·Phase: PHASE1
-
CYP2C19 Genetic Polymorphism on the Accuracy of Proton-Pump Inhibitor Testing
NCT00354757 ·Status: COMPLETED ·Phase: PHASE4
-
Safety, Pharmacokinetics and Pharmacodynamics of the Two Esomeprazole Formulations
NCT03372850 ·Status: UNKNOWN ·Phase: PHASE1
-
Exploratory Study to Standard Triple Therapy With Tegoprazan(by Dose) in H. Pylori Positive Patients
NCT05933031 ·Status: UNKNOWN ·Phase: PHASE2
-
Comparative Study Evaluating Safety and Effectiveness of ( Proton Pump Inhibitor Versus Vonoprazan ) Based Triple Therapy With or Without Zinc to Eradicate H. Pylori Infection
NCT07275827 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3
-
High Dose PPI Triple Therapy Versus Sequential Therapy for Helicobacter Pylori Eradication
NCT01888237 ·Status: COMPLETED ·Phase: PHASE4
-
A Comparative Study of Proton-pump Inhibitor Tests for Chinese Reflux Patients in Relation to the CYP2C19 Genotypes
NCT00681005 ·Status: COMPLETED ·Phase: NA
-
Vonoprazan in Helicobacter Pylori Treatment an RCT
NCT04901663 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy of Proton Pump Inhibitor in Prevention of Clopidogrel-related Peptic Ulcer
NCT01138969 ·Status: COMPLETED ·Phase: PHASE2
-
A RCT of the Efficacy of Vonoprazan 20mg QD in the Treatment of Helicobacter Pylori Infection
NCT05590286 ·Status: UNKNOWN ·Phase: PHASE4
-
A Comparison of Two Therapeutic Strategies for the Treatment of Aspirin-associated Peptic Ulcers
NCT01353144 ·Status: COMPLETED ·Phase: PHASE4
-
Role of Pain Modulation in GERD Patients Who Failed Standard Dose Proton Pump Inhibitors (PPI)
NCT00251732 ·Status: COMPLETED ·Phase: PHASE4
-
Potassium-Competitive Acid Blocker Versus Proton Pump Inhibitor as A Part of Bismuth Based Quadruple Therapy for Treatment of Helicobacter Pylori Infection
NCT07165444 ·Status: RECRUITING ·Phase: NA
-
Efficacy/Safety Study as H. Pylori Eradication of Triple Therapy for 7 Days Treatment
NCT02084420 ·Status: COMPLETED ·Phase: PHASE3
-
Tegoprazan- Versus PPI-based H. Pylori Eradication
NCT06682533 ·Status: RECRUITING
-
A Study to Evaluate Effects of Proton-pump Inhibitor on Acalabrutinib Capsule When Administered Orally With COCA-COLA in Healthy Participants
NCT04489797 ·Status: COMPLETED ·Phase: PHASE1
-
A Double-blind, Comparative Study in Patients With Gastric Ulcer to Evaluate the Efficacy of Combination Use of E0671 and Rabeprazole Sodium
NCT00125736 ·Status: COMPLETED ·Phase: PHASE4
-
AGN 201904 Versus Esomeprazole in the Prevention of Aspirin-induced Stomach or Upper Intestinal Damage in Healthy Volunteers
NCT00325715 ·Status: COMPLETED ·Phase: PHASE1
-
High Dose Esomeprazole Na for Prevention of Rebleeding After Successful Endoscopic Therapy of a Bleeding Peptic Ulcer
NCT01757275 ·Status: COMPLETED ·Phase: PHASE3
-
Trial of Itopride 150mg Once a Day Versus Itopride 50 mg Thrice a Day; in Patients With Functional Dyspepsia
NCT06217393 ·Status: COMPLETED ·Phase: PHASE3
-
The Effect of Dual Eradication Therapy vs PPI on Gastrointestinal Bleeding in ACS Patients
NCT04728516 ·Status: RECRUITING ·Phase: PHASE4
-
Vonoprazan for Helicobacter Pylori Eradication in Adolescents
NCT06162949 ·Status: COMPLETED ·Phase: PHASE3
-
High Dose Versus Standard Dose Proton Pump Inhibitor (PPI) in High-risk Bleeding Peptic Ulcers After Combined Endoscopic Treatment
NCT00709046 ·Status: UNKNOWN ·Phase: NA
-
Long-term Oral Esomeprazole for Prevention of Peptic Ulcer Rebleeding in High-risk Patients
NCT02456012 ·Status: COMPLETED ·Phase: PHASE4