Active Surveillance of Papillary Thyroid Microcarcinoma
NCT02609685 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 216
Last updated 2026-05-07
Summary
The purpose of this study is to better understand the outcomes of active surveillance (observation) instead of immediate surgery, which is the current standard of care for papillary thyroid microcarcinoma (PTMC). Patients with a 1.5 cm or smaller thyroid nodule(s) with papillary thyroid carcinoma will be eligible for the study.
Conditions
- Papillary Thyroid Microcarcinoma
Interventions
- OTHER
-
Active Surveillance
Subjects will be actively observed for disease progression (condition worsens) instead of receiving immediate surgery, considered standard of care.
Sponsors & Collaborators
-
Cedars-Sinai Medical Center
lead OTHER
Principal Investigators
-
Allen Ho, MD · Cedars-Sinal Medical Center
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- OTHER
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-05-13
- Primary Completion
- 2030-12-31
- Completion
- 2030-12-31
Countries
- United States
Study Locations
More Related Trials
-
Necessity of TSH Suppression Therapy in Active Surveillance for Thyroid Cancer Patients.
NCT06971965 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Study of the Anti-angiogenesis Agent AG-013736 in Patients With Metastatic Thyroid Cancer
NCT00094055 ·Status: COMPLETED ·Phase: PHASE2
-
Relationship of Preoperative Parathyroid Hormone (PTH) and Ex-Vivo Gamma Counts in Minimally Invasive Parathyroidectomy
NCT01539486 ·Status: COMPLETED
-
Predictive Factors of Clinical, Laboratory and Imaging Findings Routinely Used in Diagnosing Thyroid Cancer
NCT01074684 ·Status: COMPLETED
-
No Prognostic or Molecular Disparity Between Synchronous and Metachronous Metastases in Differentiated Thyroid Cancer: Insight From Middle Eastern Cohort
NCT07115810 ·Status: COMPLETED
-
Minimally Invasive Treatments of the Thyroid
NCT06333587 ·Status: RECRUITING
-
Coexisting Thyroid Disease and Hyperparathyroidism
NCT01306916 ·Status: COMPLETED
-
Intervention to Decrease Overtreatment of Patients With Low-risk Thyroid Cancer
NCT06073223 ·Status: COMPLETED ·Phase: NA
-
Treatment for Patients With Metastatic Thyroid Cancer
NCT00176748 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Collect Information About the Use of Redifferentiating Medications as a Standard Treatment for Thyroid Cancer
NCT05733013 ·Status: RECRUITING
-
Determination of Pronostics Factors for Advanced Thyroid Carcinoma (pT3 pT4 or M1 at Diagnosis)
NCT02156362 ·Status: UNKNOWN ·Phase: NA
-
Sentinel Lymphnode in Patients With Papillary Thyroid Carcinoma and in Patients With Suspected Thyroid Neoplasia
NCT01089335 ·Status: COMPLETED
-
Impact of Conventional Treatments and Clinical Variables on Thyroid Cancer
NCT05752604 ·Status: RECRUITING
-
Prediction of Lymph Node Metastasis in Patients With Thyroid Malignancy by a New Scale
NCT06286631 ·Status: RECRUITING
-
Thyroglobulin Point of Care Assay for Rapid Detection of Metastatic Differentiated Thyroid Carcinoma
NCT05078853 ·Status: COMPLETED
-
Urinary Exosomal Biomarkers of Thyroglobulin and Galectin-3 for Prognosis and Follow-up in Patients of Thyroid Cancer
NCT04948437 ·Status: ACTIVE_NOT_RECRUITING
-
This Study is Mainly About Finding Incidence Among Other Factors of Thyroid Cancer in Patient with Benign Disease As MNG to Early Discover of the Malignancy to Save the Patient from Aggressive Procedure
NCT06730971 ·Status: NOT_YET_RECRUITING
-
Prevalence and Predictors of Incidental Thyroid Carcinoma in Patients With Graves' Disease Undergoing Thyroidectomy.
NCT07059507 ·Status: RECRUITING
-
Precision Thyroid Cancer Surgery With Molecular Fluorescent Guided Imaging
NCT03470259 ·Status: COMPLETED ·Phase: PHASE1
-
More Than 50% of Unifocal cN0 T1b/Small T2 Papillary Thyroid Carcinoma May Require Completion Thyroidectomy if Nodal Status is Evaluated
NCT06439745 ·Status: COMPLETED
-
Surgery for Thyroid Cancer With or Without Autofluorescence to Prevent Hypoparathyroidism
NCT06222606 ·Status: RECRUITING ·Phase: NA
-
Study Of AG-013736 In Patients With 131I-Refractory Thyroid Cancer
NCT00389441 ·Status: COMPLETED ·Phase: PHASE2
-
Shared Care Thyroid Cancer Follow-up Utilizing Thyroid Cancer Assessment Reminder System (TCARS) Study - A Pilot Study.
NCT05510934 ·Status: RECRUITING
-
The Evaluation of the Diagnostic Properties of Intra-operative In-situ Thyroglobin Levels of Cervical Lymph Nodes, in the Discrimination Between Benign and Malignant Lymph Nodes in Thyroid Cancer: a Prospective Multicentre Study.
NCT02602717 ·Status: UNKNOWN ·Phase: NA
-
Evaluation of Hypothyroidism Incidence After Breast Cancer Supraclavicular Irradiation
NCT02824016 ·Status: COMPLETED ·Phase: NA