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Effect of Premedication on Success of Inferior Alveolar Nerve Block Injection

NCT02601911 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2016-09-20

No results posted yet for this study

Summary

The aim of this study is effect of premedication on success of inferior alveolar nerve block injection. Sixty healthy adult volunteers including criteria, are participating. The patients will be divided into 3 groups and will be randomly given one of premedications including 1) 10 mg Ketorolac, 2) 10 mg Ketorolac plus 1000mg Acetaminophen, and 3)Placebo, 45 minutes before applying the injection. All patients will receive standard Inferior Alveolar Nerve Block injection . Patients with no lip numbness and positive responses to cold and electric pulp tests would be excluded from the study. Endodontic access preparation will be initiated 15 minutes after Inferior Alveolar Nerve Block injection. Pain during treatment will be recorded using a Heft parker Visual Analog Scale(VAS). Success will be considered as no or mild pain (VAS≤54) during caries/dentin removal, access cavity preparation and working lengths measurements. Data will be analysed using Mann-U-Whitney and Kruskal-wallis tests.

Conditions

  • Irreversible Pulpitis

Interventions

DRUG

Ketorolac Tromethamine

10 mg Ketorolac tromethamine is applied 45 minutes before the injection.

DRUG

Acetaminophen

10 mg Ketorolac tromethamine/ 1000mg Acetaminophen application before injection.

OTHER

Placebo

This group receive the caplet including placebo 45 minutes before the injection.

Sponsors & Collaborators

  • Azad University of Medical Sciences

    lead OTHER

Principal Investigators

  • Nahid Mohammadzadeh Akhlaghi, DDS, MDS · Associate Professor

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-09-30
Primary Completion
2016-05-31
Completion
2016-06-30

Countries

  • Iran

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02601911 on ClinicalTrials.gov