Retrospective Analysis of Response Markers and Adverse Events in Melanoma Patients Treated With Pembrolizumab
NCT02600169 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 150
Last updated 2024-05-06
Summary
This study is a retrospective cohort study. A database will be created from the data available of all patients that have participate in the named patient program for pembrolizumab in the Netherlands. This database will be used for analysis of response markers and for an evaluation of adverse events.
Conditions
Interventions
- DRUG
-
Pemprolizumab
All patients in this study have received treatment with pembrolizumab for the indication of an advanced melanoma.
Sponsors & Collaborators
-
University Medical Center Groningen
lead OTHER
Principal Investigators
-
G.A.P. Hospers, MD, PhD · University Medical Center Groningen
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-07-31
- Primary Completion
- 2019-04-30
- Completion
- 2019-04-30
Countries
- Netherlands
Study Locations
More Related Trials
-
Profiling of Circulating Immune Cells to Uncover Response Signatures to Anti-PD1 Immunotherapy in Melanoma Patients
NCT06154668 ·Status: RECRUITING
-
Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.
NCT05727904 ·Status: RECRUITING ·Phase: PHASE3
-
Study to Compare the Effect of Ipilimumab Retreatment With That of Chemotherapy in Advanced Melanoma
NCT01709162 ·Status: TERMINATED ·Phase: PHASE2
-
Clinical Study of CMP-001 in Combination With Pembrolizumab or as a Monotherapy
NCT02680184 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Compare the Administration of Pembrolizumab After Surgery Versus Administration Both Before and After Surgery for High-Risk Melanoma
NCT03698019 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Understanding Immunotherapy Resistance Mechanisms in Advanced Melanoma
NCT02694965 ·Status: COMPLETED
-
Pembrolizumab and Ibrutinib in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery
NCT03021460 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Low Dose Ipilimumab With Pembrolizumab in Treating Patients With Melanoma That Has Spread to the Brain
NCT03873818 ·Status: COMPLETED ·Phase: PHASE2
-
Long Term Quality of Life in Melanoma Patients in Netherlands
NCT03450876 ·Status: COMPLETED
-
Neoadjuvant Pembrolizumab for Unresectable Stage III and Unresectable Stage IV Melanoma
NCT02306850 ·Status: COMPLETED ·Phase: PHASE2
-
Induction Therapy With Vemurafenib and Cobimetinib to Optimize Nivolumab and Ipilimumab Therapy
NCT02968303 ·Status: UNKNOWN ·Phase: PHASE2
-
Immune Predictors of Response to Pembrolizumab Therapy in Stage IV Melanoma Patients
NCT02744209 ·Status: TERMINATED
-
Talimogene Laherparepvec With Pembrolizumab in Melanoma Following Progression on Prior Anti-PD-1 Based Therapy (MASTERKEY-115) (Mk-3475-A07/KEYNOTE-A07).
NCT04068181 ·Status: COMPLETED ·Phase: PHASE2
-
Trial of Pembrolizumab and Radiotherapy in Melanoma
NCT02562625 ·Status: TERMINATED ·Phase: PHASE2
-
Talimogene Laherparepvec and Pembrolizumab in Treating Patients With Stage III-IV Melanoma
NCT02965716 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Intratumoral Application of L19IL2 in Patients With Malignant Melanoma
NCT01253096 ·Status: COMPLETED ·Phase: PHASE2
-
Immune Modulation Study in Patients With Metastatic Melanoma Treated With Anti-PD1 Monoclonal Antibodies
NCT02626065 ·Status: COMPLETED ·Phase: PHASE4
-
Phase 1B Study Evaluating Alternative Routes of Administration of CMP-001 in Combination With Pembrolizumab in Participants With Advanced Melanoma
NCT03084640 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Pembrolizumab (MK-3475) Versus Placebo After Complete Resection of High-Risk Stage III Melanoma (MK-3475-054/1325-MG/KEYNOTE-054)
NCT02362594 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Pembrolizumab TX-naive Distant Mets Melanoma and Use of (C11-AMT) PET at Baseline as Imaging Biomarker
NCT03089606 ·Status: COMPLETED ·Phase: PHASE2
-
Immunologic Determinants of Response to Pembrolizumab (MK-3475) in Advanced Melanoma (MK-3475-161/KEYNOTE-161)
NCT03407170 ·Status: TERMINATED ·Phase: PHASE2
-
Immunophenotyping of Melanoma Patients on Treatment With Pembrolizumab
NCT02909348 ·Status: COMPLETED
-
Pembrolizumab and Ipilimumab After Prior Immunotherapy for Melanoma
NCT02743819 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Denosumab + PD-1 in Subjects With Stage III/ IV Melanoma
NCT03620019 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Subcutaneous Nivolumab + Relatlimab Fixed-dose Combination (FDC) in Previously Untreated Metastatic or Unresectable Melanoma
NCT05625399 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3