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Prevention and Early Detection Biomarkers of Adenomas and CRC Lesions During CRC Screening

NCT02596113 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 92

Last updated 2019-03-13

No results posted yet for this study

Summary

The investigators designed a prospective study to evaluate the predictive ability of detection of mutations in genes involved in carcinogenesis of the colon (eg hMLH1, K-Ras, B-Raf, ccfDNA) in a sample of Greek population presents for conducting colonoscopy in the context of screening under international CRC prevention instructions. This investigation will be carried out in individuals in normal risk in order to study specific mutations (in blood and tissue) to draw reliable conclusions about whether we can detect (with greater sensitivity and specificity) patients with precancerous lesions or CRC with a simple blood test thereby reducing the cost and side effects of repeated endoscopic procedures.

Conditions

Sponsors & Collaborators

  • National and Kapodistrian University of Athens

    collaborator OTHER

  • Evangelismos Hospital

    lead OTHER

Principal Investigators

  • Nikos Viazis, Director · Evangelismos Hospital

Eligibility

Min Age
50 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-07-31
Primary Completion
2017-06-30
Completion
2018-05-31

Countries

  • Greece

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02596113 on ClinicalTrials.gov