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Surgery in Early Life and Child Development at School-entry: A Population-based Study

NCT02595801 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 188628

Last updated 2015-11-17

No results posted yet for this study

Summary

The central hypothesis is that surgery and anesthesia exposure in children with immature structural and functional brain development has long-term adverse effects on child development at school-entry compared with children not exposed to anesthesia.

The secondary hypothesis is that frequency of surgery and anesthesia exposure in children with immature structural and functional brain development has a dose-dependent association with worsened child development outcomes at school-entry.

The overall objective is to investigate the association between surgery/anesthesia exposure(s) in children in Ontario and major child development outcomes (physical health and well being, social competence, emotional maturity, and language and cognitive development) at school entry as measured by the Early Development Instrument.

Conditions

  • Surgery in Early Childhood

Interventions

OTHER

Surgery in early childhood

Surgical interventions in early childhood (prior to completion of Early Development Instrument)

Sponsors & Collaborators

  • McMaster University

    collaborator OTHER

  • Institute for Clinical Evaluative Sciences

    collaborator OTHER

  • The Hospital for Sick Children

    lead OTHER

Eligibility

Max Age
6 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-08-31
Primary Completion
2015-11-30
Completion
2015-11-30

Countries

  • Canada

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02595801 on ClinicalTrials.gov