The Role of Orexin in Human Panic Disorder
NCT02593682 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 3
Last updated 2021-07-02
Summary
The purpose of this study is to provide some information (pilot data) about whether the study drug, suvorexant, (1) affects levels of orexin in people with panic disorder, and (2) is associated with decreased panic symptoms in response to a carbon dioxide (CO2) challenge.
Conditions
- Panic Disorder
Interventions
- DRUG
-
suvorexant
- DRUG
Sponsors & Collaborators
-
University of California, San Francisco
lead OTHER
Principal Investigators
-
Andrew Goddard, MD · University of California, San Francisco
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-05-31
- Primary Completion
- 2020-03-13
- Completion
- 2020-03-13
Countries
- United States
Study Locations
More Related Trials
-
Effects of Ondansetron in Obsessive-compulsive and Tic Disorders
NCT03239210 ·Status: COMPLETED ·Phase: PHASE4
-
Costs of Lost Productive Time Among Korean Workers With Panic Disorder and Effect of Treatment With Paroxetine Controlled Release
NCT00492414 ·Status: UNKNOWN ·Phase: PHASE4
-
Exposure, D-Cycloserine Enhancement, and Genetic Modulators in Panic Disorder
NCT00790868 ·Status: COMPLETED ·Phase: PHASE2
-
A 10-Week, Open-Label, Flexible Dose Adaptive Study Evaluating the Efficacy of Vortioxetine in Subjects With Panic Disorder
NCT02395510 ·Status: COMPLETED ·Phase: PHASE4
-
Pilot Study of ORG 25935 Modulation of Ketamine-induced Behavioral and Cognitive Effects in Healthy Male Subjects
NCT00700076 ·Status: COMPLETED ·Phase: PHASE1
-
Breathing Regulation Training for Individuals With Panic Disorder
NCT00183521 ·Status: COMPLETED ·Phase: NA
-
A Double-blind, Placebo-controlled Clinical Trial of Fluvoxamine for Symptomatic Individuals With COVID-19 Infection
NCT04342663 ·Status: COMPLETED ·Phase: PHASE2
-
Neurobiological Mechanisms in Panic Disorder
NCT00103987 ·Status: COMPLETED
-
A Study of Pregabalin (Lyrica) Augmentation in Serotonin Reuptake Inhibitor-Refractory Obsessive Compulsive Disorder
NCT00994786 ·Status: COMPLETED ·Phase: PHASE4
-
Evaluation of Substance P Neurotransmission in Panic Disorder by PET Imaging of NK1 Receptors With [18F]SPA-RQ
NCT00088738 ·Status: COMPLETED ·Phase: PHASE1
-
Trial of Oral SNC-102 in Subjects With Combat-Related Posttraumatic Stress Disorder
NCT02384369 ·Status: WITHDRAWN ·Phase: PHASE2
-
Evaluation of Safety and Pharmacodynamics of OP0201 Compared to Placebo in Healthy Adults
NCT03828149 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase 2 Study of BNC210 for the Acute Treatment of Social Anxiety Disorder
NCT05193409 ·Status: COMPLETED ·Phase: PHASE2
-
Pilot Study of RR-HNK in OCD
NCT06575075 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Safety and Efficacy of HB-1 for Panic Disorder
NCT05071430 ·Status: COMPLETED ·Phase: PHASE2
-
Neurobehavioral Correlates of Caffeine on Anxiety, Avoidance and Interoception in Healthy Individuals and Panic Disorder.
NCT06145490 ·Status: COMPLETED ·Phase: NA
-
Examining the Usage of Dopamine Blockers in OCD Patients
NCT00496925 ·Status: COMPLETED
-
Effects of Caffeine on Anxiety, Emotional Processing, Approach-avoidance Behavior, and Interoception in Panic Disorder
NCT05261594 ·Status: COMPLETED ·Phase: NA
-
Neural Effects of Cognitive-behaviour Therapy in Panic Disorder
NCT03251235 ·Status: COMPLETED ·Phase: NA
-
Predicting Treatment Response to Exposure Therapy Using Carbon Dioxide
NCT03925987 ·Status: COMPLETED ·Phase: NA
-
An Open-label Study to Investigate the Absorption, Metabolism and Excretion of Radiolabeled PD 0332334 in Six Healthy Male Volunteers
NCT00537615 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy of BNC210 in Acute, As-needed Treatment of Anxiety in Social Anxiety Disorder - 1
NCT06510504 ·Status: COMPLETED ·Phase: PHASE3
-
Long-term Safety Study of Adjunctive Troriluzole in Subjects With Obsessive Compulsive Disorder
NCT04708834 ·Status: TERMINATED ·Phase: PHASE3
-
Evaluation of Clonazepam and Paroxetine for Panic Disorder With Depression
NCT00031317 ·Status: COMPLETED ·Phase: PHASE4
-
A Study in Healthy Men to Test Whether BI 1358894 Reduces Druginduced Panic Symptoms
NCT03904576 ·Status: COMPLETED ·Phase: PHASE1