Evaluation of Substance P Neurotransmission in Panic Disorder by PET Imaging of NK1 Receptors With [18F]SPA-RQ
NCT00088738 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 84
Last updated 2017-07-02
Summary
This study is designed to observe the effects of a panic attack in patients with panic disorders and to demonstrate the involvement of Substance P in panic disorder, and thereby, further our understanding of its role in this illness. We will measure levels of Substance P in the brain by obtaining pictures of the brain using PET and MRI....
Conditions
- Panic Disorder
- Healthy
Interventions
- DRUG
-
[18F] SPA-RQ
Sponsors & Collaborators
-
National Institute of Mental Health (NIMH)
lead NIH
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2004-07-27
- Completion
- 2008-09-10
Countries
- United States
Study Locations
More Related Trials
-
Pharmaco-Neuroimaging Studies of Approach/Avoidance Behaviors and Post-Mortem Studies: Pharmacological Manipulation
NCT05232032 ·Status: RECRUITING ·Phase: PHASE2
-
Psychodynamic Therapy for Treating Panic Disorder
NCT00128388 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Neuroimaging of Pavlovian Fear Conditioning Processes in Patients With Pathological Anxiety
NCT03498599 ·Status: UNKNOWN ·Phase: NA
-
Interactive Computer Treatment for Panic Disorder
NCT00063375 ·Status: COMPLETED ·Phase: PHASE1
-
Fast-Fail Trials in Mood and Anxiety Spectrum Disorders; Kappa Opioid Receptor Phase 2a
NCT02218736 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy of HB-1 for Panic Disorder
NCT05071430 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate Efficacy, Safety, and Tolerability of Darigabat in Participants With Panic Disorder
NCT05941442 ·Status: TERMINATED ·Phase: PHASE2
-
Treatment of Panic Disorder: Long Term Strategies
NCT00000368 ·Status: COMPLETED ·Phase: PHASE3
-
Clonazepam and Paroxetine for Rapid Treatment of Post-Traumatic Stress Disorder
NCT00025740 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of SRX246 on an Experimental Model of Fear and Anxiety in Humans
NCT02922166 ·Status: UNKNOWN ·Phase: PHASE1
-
A Study To Compare Emotional Changes In Subjects With Social Anxiety Disorder
NCT00470483 ·Status: COMPLETED ·Phase: PHASE1
-
The Efficacy and Tolerability of Duloxetine for the Treatment of Panic Disorder
NCT00438971 ·Status: COMPLETED ·Phase: PHASE4
-
The Effects of JNJ-42165279 on the Neural Basis of Anxiety Disorders in Healthy Male Volunteers
NCT01826786 ·Status: COMPLETED ·Phase: PHASE1
-
Effects of Buspar on Depressive Symptom Improvement and Neuroprotection in Patients With Anxiety Disorder
NCT01546896 ·Status: WITHDRAWN ·Phase: PHASE4
-
Antiglucocorticoid Therapy for Cognitive Impairment in Late-life Anxiety Disorders
NCT01333098 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Internet-based Exposure Therapy for Panic Disorder
NCT03061448 ·Status: COMPLETED ·Phase: NA
-
Effectiveness of Cognitive Behavioral Therapy With Panic Control Treatment for Adolescents With Panic Disorder
NCT00705380 ·Status: COMPLETED ·Phase: PHASE2
-
Long Term Treatment of Panic Disorder With Clonazepam or Paroxetine
NCT02852577 ·Status: COMPLETED ·Phase: PHASE4
-
Proof-of-concept Study to Assess the Efficacy and Safety of SRX246 in Adults With PTSD
NCT02733614 ·Status: TERMINATED ·Phase: PHASE2
-
Disruption of Memory Reconsolidating as a Treatment for Panic Disorder
NCT02631694 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study in Healthy Men to Test Whether BI 1358894 Reduces Druginduced Panic Symptoms
NCT03904576 ·Status: COMPLETED ·Phase: PHASE1
-
Treatment of Panic Disorder Among Individuals Consulting Emergency Departments for Non Cardiac Chest Pain
NCT00736346 ·Status: UNKNOWN ·Phase: NA
-
Improving Quality of Primary Care for Patients With Anxiety and/or Panic Disorders
NCT00102427 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Efficacy and Mechanisms of Psychosocial Treatments for Panic Disorder
NCT04366011 ·Status: COMPLETED ·Phase: NA
-
Characterize The Modulatory Effects Of Dopamine D2/D3 Receptor Agonist And Antagonist Drugs On Compulsive Behaviors
NCT00471588 ·Status: COMPLETED ·Phase: PHASE1