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Effect of Broccoli Sprout Extract on Keratinocyte Differentiation in Normal Skin

NCT02592954 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 5

Last updated 2017-12-06

No results posted yet for this study

Summary

Adult participants will apply a broccoli sprout extract-jojoba oil compound to one arm every night under occlusion for 1 week. Jojoba oil alone will be applied to the other arm. At the end of 1 week, a 6mm punch biopsy will be taken from both arms and analyzed via polymerase chain reaction (PCR) and immunohistochemistry for differences in various skin proteins.

Conditions

  • Epidermolysis Bullosa Simplex
  • Pachyonychia Congenita

Interventions

DRUG

Jojoba oil with broccoli sprout extract

500nmol of broccoli sprout extract in 1ml of jojoba oil will be applied to the same arm every night under saran wrap for 1 week

DRUG

Jojoba oil (placebo)

1ml of jojoba oil will be applied to the same arm every night under saran wrap for 1 week

Sponsors & Collaborators

Principal Investigators

  • Bernard Cohen, MD · Professor of Dermatology

Study Design

Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-09-30
Primary Completion
2016-12-31
Completion
2016-12-31

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02592954 on ClinicalTrials.gov