Evaluation of Latanoprost Combined With Fractional Erbium- YAG Laser
NCT06239324 · Status: RECRUITING · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 70
Last updated 2024-04-16
Summary
Alopecia areata (AA) an autoimmune disorder of hair follicles results in varying degrees of scalp, facial and body hair loss.
Clinically, patients' presentation varies from patchy circumscribed scalp involvement to total body and scalp hair loss affects up to 2% of the general population.
The exact pathobiology of AA has still remained elusive, while the common theory is the collapse of the immune privilege of the hair follicle caused by immunological mechanism. Multiple genetic, environment factors and psychological stress contribute to the pathogenesis of Alopecia Areata .
Recent insights into the pathogenesis of AA have led to the development of new treatment strategies, such as Janus kinase inhibitors, biologics and several small molecular agents. In addition, modern therapies for AA, including antihistamines, platelet-rich plasma injection
Conditions
Interventions
- DRUG
-
Latanoprost
Comparing between Erbium YAG laser assisted drug delivery of latanoprost versus transepidermal latanoprost delivery by microneedling in alopecia areata treatment for all participants.
Sponsors & Collaborators
-
Egymedicalpedia
lead INDUSTRY
Principal Investigators
-
Soheir AbdelHamid Ali, Assist. Prof. · Department of dermatology , Venerolgy and Andrology Faculty of Medicine Qena university
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 30 Years
- Max Age
- 35 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-02-01
- Primary Completion
- 2024-04-20
- Completion
- 2024-05-01
Countries
- Egypt
Study Locations
More Related Trials
-
Evaluation of the Effect of Topical Calcipotriol Versus Platelet-Rich Plasma
NCT05954104 ·Status: COMPLETED ·Phase: NA
-
Comparison of Microneedling Along With Topical Vitamin D3 Versus Microneedling in Alopecia Areata
NCT07243977 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Efficacy of Fractional CO2 Laser as a Mono- or Adjuvant Therapy for Alopecia Areata
NCT04003376 ·Status: UNKNOWN ·Phase: PHASE4
-
Methotrexate Versus Triamcinilone Acetonide in Treatment of Recalcitrant Alopecia Areata
NCT06088147 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Safety and Efficacy of Doses of LEO 43204 Once Daily for Two Consecutive Days on Full Balding Scalp in Subjects With Actinic Keratosis
NCT02100813 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Combined CO2 Fractional Laser With Bimatoprost 0.03% Treatment of Alopecia Areata
NCT05600673 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
The Efficacy and Safety of Different Concentrations of Localized Injections of Steroids in the Treatment of Alopecia Areata
NCT01246284 ·Status: COMPLETED ·Phase: NA
-
The Effect of Platelet Rich Plasma on Non-scarring Alopecia
NCT03689452 ·Status: COMPLETED ·Phase: NA
-
Fraxel Laser for Alopecia
NCT03284021 ·Status: WITHDRAWN ·Phase: NA
-
The Comparison Study of Intralesional Botulinum Toxin A and Corticosteroid Injection for Alopecia Areata
NCT00999869 ·Status: UNKNOWN ·Phase: NA
-
Fractional Laser Versus Radiofrequency in Androgenetic Alopecia
NCT05435625 ·Status: UNKNOWN ·Phase: NA
-
1565nm Non-ablative Fractional Laser Treat Alopecia Areata
NCT05744505 ·Status: UNKNOWN ·Phase: NA
-
Combined Microneedling and Topical Pentoxifylline Vesrus Intalesional Pentoxifylline in Treatment of Alopecia Areata: Intra-indiviual Comparative Study
NCT05502952 ·Status: UNKNOWN ·Phase: NA
-
LEO 124249 Ointment in the Treatment of Alopecia Areata
NCT02561585 ·Status: COMPLETED ·Phase: PHASE2
-
Comparison of Microneedling vs. Autologous Concentrated Growth Factor for the Treatment of Female Androgenetic Alopecia
NCT06218394 ·Status: RECRUITING ·Phase: NA
-
Combined Microneedling With Either 1% Lactic Acid Solution or Vitamin D3 or Triamcinolone Acetonide in The Treatment of Alopecia Areata
NCT06327581 ·Status: RECRUITING ·Phase: NA
-
Characterization And Clinical Outcomes of AA Patients Treated With Ritlecitinib
NCT06531109 ·Status: RECRUITING
-
Superficial Cryotherapy Versus Microneedling in Alopecia Areata
NCT04680234 ·Status: COMPLETED ·Phase: NA
-
Efficacy and Safety of LEO 43204 in Field Treatment of Actinic Keratosis on Balding Scalp Including 12-month Follow-up
NCT02549352 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluation of Serum Levels of Interlukin-15 and Interlukin-21 in Patients With Alopecia Areata
NCT05910138 ·Status: UNKNOWN ·Phase: NA
-
Comparative Study for Treatment of Alopecia Areata Using Carboxytherapy and Intralesional Steroids
NCT04228029 ·Status: UNKNOWN ·Phase: PHASE4
-
Phase 2 Trial of BNZ-1 in Patients With Moderate to Severe Alopecia Areata
NCT03532958 ·Status: WITHDRAWN ·Phase: PHASE2
-
Topical 5% Minoxidil and Potent Topical Corticosteroid Versus Intralesional Corticosteroid in the Treatment of Alopecia Areata
NCT03535233 ·Status: COMPLETED ·Phase: PHASE4
-
Alefacept in Patients With Severe Scalp Alopecia Areata
NCT00167102 ·Status: COMPLETED ·Phase: NA
-
Clinical Application of Stem Cell Educator Therapy in Alopecia Areata
NCT04011748 ·Status: UNKNOWN ·Phase: PHASE2