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Hunting for the Off-Target Properties of Ticagrelor on Endothelial Function in Humans (HI-TECH)

NCT02587260 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 54

Last updated 2017-02-13

No results posted yet for this study

Summary

The purpose of this randomized, cross-over study, is to ascertain if ticagrelor, but not prasugrel or clopidogrel, is associated to an improved endothelial function as assessed with peripheral arterial tonometry and markers of endothelial function measurement in post-ACS patients.

Conditions

Interventions

DRUG

Ticagrelor

Comparison of ticagrelor with respect to prasugrel and clopidogrel in a different sequence

DRUG

Prasugrel

Comparison of ticagrelor with respect to prasugrel and clopidogrel in a different sequence

DRUG

Clopidogrel

Comparison of ticagrelor with respect to prasugrel and clopidogrel in a different sequence

Sponsors & Collaborators

Principal Investigators

  • Marco Valgimigli, MD, PhD · Erasmus Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-12-17
Primary Completion
2017-02-10
Completion
2017-02-10

Countries

  • Italy
  • Netherlands
  • Spain
  • Switzerland

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02587260 on ClinicalTrials.gov