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The Safety and Efficacy of Epidural Oxycodone

NCT02573909 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2023-03-16

No results posted yet for this study

Summary

There are conflicting results in earlier studies concerning the safety and efficacy of epidural oxycodone. In a study by Bäcklund and colleagues, epidural oxycodone was as effective as intravenous oxycodone, so they did not recommend epidural use of oxycodone. In another study, Yanagidate and Dohi reported that oxycodone was as effective in pain treatment with double dose compared to epidural morphine. In our previous study, epidural oxycodone provided safe and effective pain relief when compared to intravenous oxycodone.

In the present study, the aim was to compare the efficacy and safety of epidural or intravenous oxycodone in patients undergoing elective gynecological surgery with planned epidural pain treatment.

Conditions

  • Pain, Postoperative

Interventions

DRUG

Oxycodone intravenously

Oxycodone intravenously 0,1mg/kg

DRUG

Oxycodone epidurally

Oxycodone 0,1 mg epidurally

Sponsors & Collaborators

  • Admescope Ltd

    collaborator INDUSTRY

  • Kuopio University Hospital

    lead OTHER

Principal Investigators

  • Merja Kokki, PhD · Kuopio University Hospital, Kuopio, Finland

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-01-01
Primary Completion
2023-12-31
Completion
2023-12-31

Countries

  • Finland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02573909 on ClinicalTrials.gov