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Reversal of Ketamine Pharmacodynamic Effects With Naloxone

NCT00921765 · Status: TERMINATED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 3

Last updated 2018-04-05

No results posted yet for this study

Summary

The purpose of this study is to determine whether the analgetic and other effects effect of ketamine are partly mediated through opioid receptors

Conditions

Interventions

DRUG

Saline

Saline single bolus dose followed by saline single bolus dose iv

DRUG

Saline + Ketamine

Single bolus dose of saline followed by ketamine 0.2 mg/kg bw

DRUG

Naloxone + Placebo

Single bolus dose of naloxone 0.2 mg/kg bw followed by single bolus dose of saline

DRUG

Naloxone + Ketamine

Single bolus dose of naloxone 0.2 mg/kg bw followed by single bolus dose of ketamine 0.2 mg/kg bw

Sponsors & Collaborators

  • University of Oslo

    collaborator OTHER

  • Ullevaal University Hospital

    lead OTHER

Principal Investigators

  • Olav Hustveit, MD, PhD · University of Oslo

  • Elena Landari, DDS · University of Oslo

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-12-31
Primary Completion
2017-12-31
Completion
2017-12-31

Countries

  • Norway

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00921765 on ClinicalTrials.gov