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Follow-Up Study of People Treated for Scoliosis

NCT02546479 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 5573

Last updated 2019-07-15

No results posted yet for this study

Summary

Background:

Scoliosis is a curving of the spine. It usually happens in girls when they are children and teens. Doctors often use x-rays to diagnose it. The x-rays give low radiation. This may increase the risk that those young women get cancer later in life. Researchers want to learn more about this risk. They will look data that has already been collected.

Objectives:

To study cancer risks of repeated low radiation from x-rays for scoliosis. Also, to study death risks related to certain scoliosis patient characteristics. These include causes, kinds of curvature, and kinds of treatment.

Eligibility:

Medical records of women from past scoliosis studies.

Design:

This U.S. Scoliosis Cohort includes more than 5,000 women who were diagnosed between 1912 and 1965.

Data were collected on these women in the 1980s and 1990s. These came from medical records, radiology log books, and x-ray films. Researchers found out where participants were, including if they were dead. Some women were given a follow-up questionnaire.

Researchers want to find out where participants are today. They want to identify new deaths of participants. They want to find out their causes of death. This data will be added to other databases.

Conditions

  • Breast and Other Cancer Incidence and Mortality
  • All Cause Mortality
  • Circulatory Disease Mortality
  • Respiratory Disease Mortality

Sponsors & Collaborators

  • Social & Scientific Systems Inc.

    collaborator INDUSTRY

  • National Cancer Institute (NCI)

    lead NIH

Principal Investigators

  • Michele M Doody · National Cancer Institute (NCI)

Eligibility

Min Age
50 Years
Max Age
95 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-09-09
Primary Completion
2016-08-16
Completion
2019-07-11

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02546479 on ClinicalTrials.gov