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Validation of a Purine Biosensor in Detecting Acute Cerebral Ischaemia: Carotid Endarterectomy Model in SMARTChip

NCT02545166 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 198

Last updated 2022-07-12

No results posted yet for this study

Summary

This study will validate the sensitivity of a purine biosensor (SMARTChip) in detecting acute cerebral ischaemia in a group of patients undergoing elective carotid endarterectomy. The study will also investigate whether blood purine levels are indicative of future risk of stroke by comparing pre-operative blood purine levels in carotid endarterectomy patients (high risk group) and blood purine levels in a group of age and sex-matched controls.

Conditions

Sponsors & Collaborators

  • University Hospitals of North Midlands NHS Trust

    collaborator OTHER

  • University Hospitals Coventry and Warwickshire NHS Trust

    lead OTHER

Principal Investigators

  • Christopher HE Imray, MB BS PhD · University Hospitals Coventry and Warwickshire NHS Trust

  • Jack Fairhead, BM BCh BA · University Hospitals of North Midlands NHS Trust

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-03-16
Primary Completion
2022-05-20
Completion
2022-05-20

Countries

  • United Kingdom

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02545166 on ClinicalTrials.gov