Antiviral Efficacy of the Combination Treatment With Poly IC and Entecavir for Chronic Hepatitis B
NCT02532413 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 180
Last updated 2015-08-25
Summary
The purpose of this study is to investigate antiviral efficacy of the combination treatment with Poly IC and Entecavir and compare with the efficacy of Entecavir mono-therapy for chronic hepatitis B.
Conditions
Interventions
- DRUG
-
Poly IC
Poly IC can induce innate immune responses.It may enhance the antiviral efficacy of Entecavir.
- DRUG
-
Entecavir
Entecavir can inhibit the replication of HBV.
Sponsors & Collaborators
-
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
lead OTHER
Principal Investigators
-
Liang D Yang, M.D. · Huanzhong University of Science and Technology
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-07-31
- Primary Completion
- 2016-08-31
- Completion
- 2017-08-31
Countries
- China
Study Locations
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