MedTrace Logo

Pilot Study to Assess the Quantitative Dermal Transfer Efficiencies of Solids for Multiple Transfer Pathways

NCT02529748 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2019-08-15

No results posted yet for this study

Summary

Dermal transfer efficiency has been defined as the amount of material that moves from one surface to another following contact. The investigators propose to measure dermal transfer efficiency for the following pathways: (1) object to skin, (2) skin to skin, (3) skin to mouth, (4) clothing to skin, (5) gloves to skin, and (6) air to skin. First, the quantitative dermal transfer will be measured for the two selected test substances (lead, Tinopal) for each of these six pathways. The relative quantities of dermal transfer will also then be compared between the different transfer pathways (e.g., is skin to skin transfer greater or less than clothing to skin transfer?). And second, the pattern of transfer will be characterized semi-quantitatively (e.g., does dermal transfer occur consistently and evenly to the skin from different reservoirs?).

Conditions

  • Environmental Exposure

Interventions

OTHER

Participants for Surface Skin Sampling

Skin wipe samples will be collected to quantify the amount of the test substances transferred to and from the surface of the participants' skin.

OTHER

Elemental metallic lead

Consumer product fishing tackle made of elemental lead will be handled by the participants.

OTHER

Tinopal

Tinopal, a fluorescent tracer, will be handled by the participants.

Sponsors & Collaborators

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-08-01
Primary Completion
2019-07-31
Completion
2019-07-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02529748 on ClinicalTrials.gov