Safety and Efficacy Evaluation of iAPA-DC/CTL Combined Gemcitabine Therapy on Advanced Pancreatic Cancer
NCT02529579 · Status: UNKNOWN · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 187
Last updated 2015-08-20
Summary
The aim of this study is to evaluate the safety and efficacy of iAPA-DC/CTL combined gemcitabine therapy on advanced pancreatic cancer.
Conditions
- Carcinoma, Pancreatic Ductal
Interventions
- OTHER
-
iAPA-DC/CTL adoptive cellular immunotherapy
twice DC cell infusion and CTL cell infusion for 6 times
- DRUG
-
standard Gemcitabine therapy
Sponsors & Collaborators
-
ImmunoGene Biotechology Co.,Ltd
collaborator UNKNOWN -
Changhai Hospital
lead OTHER
Principal Investigators
-
Zhaoshen Ii, MD · Changhai Hosptial,Second Military medical University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-06-30
- Primary Completion
- 2018-12-31
- Completion
- 2019-12-31
Countries
- China
Study Locations
More Related Trials
-
Combination of Icotinib and Gemcitabine as First-line Treatment in Pancreatic Cancer
NCT02024633 ·Status: UNKNOWN ·Phase: PHASE1
-
Gemcitabine and Radiation Therapy in Treating Patients With Cancer of the Pancreas
NCT00010166 ·Status: COMPLETED ·Phase: PHASE2
-
Concurrent Chemoradiotherapy Combined With Immunotherapy in Patients With Potentially Resectable Pancreatic Cancer
NCT05634564 ·Status: UNKNOWN ·Phase: PHASE2
-
The Safety and Efficacy of Specific TIL-TCM Cells for Advanced Relapse-refractory or Metastatic Pancreatic Cancer
NCT05438797 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Adjuvant Intraperitoneal Gemcitabine for Resectable Pancreatic Adenocarcinoma
NCT01206296 ·Status: TERMINATED ·Phase: PHASE2
-
A Phase 1b Study of Gemcitabine and Nab-paclitaxel in Combination With IM156 in Patients With Advanced Pancreatic Cancer.
NCT05497778 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Phase 2 Trial of Gemcitabine vs S-1 vs Gemcitabine Plus Nab-paclitaxel as Adjuvant Chemotherapy of Post-operative Pancreatic Cancer Patients
NCT03278015 ·Status: UNKNOWN ·Phase: PHASE2
-
S-1 and and Gemcitabine vs Gemcitabine Alone as Adjuvant Chemotherapy for Patients With Resected Pancreatic Cancer
NCT02131493 ·Status: COMPLETED ·Phase: PHASE2
-
Decitabine and Gemcitabine for Pancreatic Cancer and Sarcoma
NCT02959164 ·Status: COMPLETED ·Phase: PHASE1
-
Dose Escalation and Dose Expansion Study of GAS in Subjects With Metastatic Pancreatic Adenocarcinoma
NCT06229496 ·Status: RECRUITING ·Phase: PHASE1
-
Simultaneous Gemcitabine and Irreversible Electroporation for Locally Advanced Pancreatic Cancer
NCT02981719 ·Status: COMPLETED ·Phase: NA
-
Safety and Efficacy of G17DT Immunogen Combined With Gemcitabine vs. Gemcitabine in the Treatment of Advanced Pancreatic Carcinoma
NCT00044031 ·Status: COMPLETED ·Phase: PHASE3
-
Iparomlimab and Tuvonralimab Combined With GC in Advanced ICC
NCT07152769 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
An Evaluation Trial About Anti-claudin18.2 the Specificity of Chimeric Antigen Receptor T Cells in the Advanced Gastric / Esophagogastric Junction Adenocarcinoma and Pancreatic Cancer Subjects
NCT05277987 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Induction Chemotherapy With Gemcitabine and Cisplatin Followed by CCRT for Unresectable Pancreatic Carcinoma
NCT01593475 ·Status: COMPLETED ·Phase: PHASE2
-
Nab-paclitaxel Plus Gemcitabine in Chinese Patients With Advanced Pancreatic Cancer
NCT02135822 ·Status: UNKNOWN ·Phase: PHASE2
-
Study of the Safety and Efficacy of TH-302 in Combination With Gemcitabine Compared With Gemcitabine Alone in Previously Untreated Patients With Pancreatic Adenocarcinoma
NCT01144455 ·Status: COMPLETED ·Phase: PHASE2
-
Neoadjuvant/Adjuvant Sintilimab, Nab-paclitaxel, and Gemcitabine for Resectable/Borderline Resectable Pancreatic Cancer
NCT05562297 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Clinical Trial Testing TH-302 in Combination With Gemcitabine in Previously Untreated Subjects With Metastatic or Locally Advanced Unresectable Pancreatic Adenocarcinoma
NCT01746979 ·Status: COMPLETED ·Phase: PHASE3
-
IN10018+ Standard Chemotherapy (+KN046) in Subjects With Advanced Pancreatic Cancer
NCT05827796 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Antigen-specific Cancer Immunotherapy (TG01) and Gemcitabine as Adjuvant Therapy in Resected Pancreatic Cancer
NCT02261714 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Application of ctDNA in Evaluation of Neoadjuvant Chemotherapy Efficacy and Exploration of Chemoresistance Mechanisms in Pancreatic Cancer
NCT05848154 ·Status: NOT_YET_RECRUITING
-
Anti-PD-1/PD-L1 Antibodies Plus Gemcitabine and Cisplatin for Advanced CCA
NCT07291063 ·Status: RECRUITING
-
Study With Gemcitabine and RTA 402 for Patients With Unresectable Pancreatic Cancer
NCT00529113 ·Status: TERMINATED ·Phase: PHASE1
-
Early Phase I Study of Autologous T Cells (EX02 CAR-T) for Unresectable Pancreatic/Bile Duct Cancer
NCT06196658 ·Status: NOT_YET_RECRUITING ·Phase: EARLY_PHASE1