Thrombosis and Neurocognition in Klinefelter Syndrome
NCT02526628 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 90
Last updated 2019-08-22
Summary
The haemostatic balance and neurocognitive capability of men with Klinefelter syndrome is compared to healthy controls by using specific biochemical assays for coagulation and fibrinolysis and a selection of neuropsychological tests and brain fMRI. Furthermore, the effect of gonadal status and any effects of long- or short-term testosterone treatment on the above mentioned parameters are investigated.
Conditions
- Klinefelter Syndrome
- Thrombosis
Sponsors & Collaborators
-
Aarhus University Hospital
collaborator OTHER -
Esbjerg Hospital - University Hospital of Southern Denmark
collaborator OTHER -
University of Southern Denmark
collaborator OTHER -
Sygehus Lillebaelt
collaborator OTHER -
University of Aarhus
lead OTHER
Principal Investigators
-
Claus H Gravholt, MD, Prof. · Department of Endocrinology and Internal Medine and Department of Molecular Medicine
-
Simon Chang, MD · Unit for Thrombosis Research
-
Anne Skakkebæk, MD, PhD · Department of Clinical Genetics
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2015-09-30
- Primary Completion
- 2019-08-21
- Completion
- 2019-08-21
Countries
- Denmark
Study Locations
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