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Evaluation of Regional Distribution of Ventilation During Labor With or Without Epidural Analgesia

NCT02523755 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2016-12-06

No results posted yet for this study

Summary

With an efficient epidural analgesia the physiological effects of pain are disabled during labor. Pain may cause an increase of minute volume, oxygen consumption and a decrease of paCO2 (Arterial CO2 pressure). The study will evaluate the lung function before and after labor with and without epidural analgesia. With more efficient breathing, the occurence of atelectasis should be reduced; this effect will be investigated in these settings for the first time with the electrical impedance tomography, which is a completely non-invasive measure.

Conditions

  • Pregnancy
  • Atelectasis

Interventions

DRUG

Epidural analgesia Ropivacaine

Measurement of regional distribution as assessed by EIT before and after injection of local anesthetics

DRUG

Absence of epidural analgesia

Measurement of regional distribution as assessed by EIT before and after delivery

Sponsors & Collaborators

  • Universitair Ziekenhuis Brussel

    lead OTHER

Principal Investigators

  • Maxim Doutreluigne, MD · Universitair Ziekenhuis Brussel

  • Laszlo L Szegedi, Prof. · Universitair Ziekenhuis Brussel

Study Design

Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-09-30
Primary Completion
2016-11-30
Completion
2016-12-31

Countries

  • Belgium

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02523755 on ClinicalTrials.gov