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MYOCARDIAL SILENT INFARCTIONS AND FIBROSIS IN FAMILIAL HYPERCHOLESTEROLEMIA (CHOLCOEUR)

NCT02517944 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 110

Last updated 2015-08-07

No results posted yet for this study

Summary

Patients with familial hypercholesterolemia (FH) at high cardiovascular risk may suffer from silent micro-infarctions (MI) before clinical coronary heart disease manifestations because of the lifetime exposure to elevated serum LDL-cholesterol levels.

The study aims to demonstrate the higher prevalence of silent myocardial infarction in a population of asymptomatic patients with familial hypercholesterolemia at high cardiovascular risk in comparison to control patients using Cardiac Magnetic Resonance sequences of delayed gadolinium enhancement.

Conditions

  • Familial Hypercholesterolemia - Heterozygous

Sponsors & Collaborators

  • Amgen

    collaborator INDUSTRY

  • Institute of Cardiometabolism and Nutrition, France

    lead OTHER

Principal Investigators

  • David Rosenbaum, MD · Study principal investigator

Eligibility

Min Age
40 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-11-30
Primary Completion
2015-09-30
Completion
2015-11-30

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02517944 on ClinicalTrials.gov