Nutritional Intervention Preconception and During Pregnancy to Maintain Healthy Glucose Metabolism and Offspring Health

Summary

The study aims to assess whether a nutritional drink taken before conception and continuing through pregnancy, assists in the maintenance of healthy glucose metabolism in the mother and promotes offspring health.

Conditions

• Hyperglycemia

Interventions

DIETARY_SUPPLEMENT

Study nutritional drink

Study nutritional drink containing a mix of micronutrients, probiotics and myo-inositol.

DIETARY_SUPPLEMENT

Standard nutritional drink

Standard nutritional drink containing a mix of micronutrients.

Sponsors & Collaborators

• National University Hospital, Singapore

  collaborator OTHER

• Auckland UniServices Ltd.

  collaborator INDUSTRY

• Institute for Human Development and Potential (IHDP), Singapore

  collaborator OTHER

• National University of Singapore

  collaborator OTHER

• Nestec Ltd.

  collaborator INDUSTRY

• University of Southampton

  lead OTHER

Principal Investigators

• Wayne Cutfield, BHB MB ChB DCH MD FRACP · The University of Auckland

• Shiao-Yng Chan, MBBChir (UK), FRCOG (UK), PhD · National University Hospital, Singapore

• Keith Godfrey, BM PhD FRCP · MRC Lifecourse Epidemiology Unit, University of Southampton

Study Design

Allocation

RANDOMIZED

Purpose

OTHER

Masking

QUADRUPLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

38 Years

Sex

FEMALE

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2015-07-31

Primary Completion

2018-10-31

Completion

2022-06-30

Countries

• New Zealand
• Singapore
• United Kingdom

Study Locations