MedTrace Logo

MRI in Patients With Kennedy Disease

NCT02501395 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 53

Last updated 2018-06-04

No results posted yet for this study

Summary

Kennedy disease is an inherited neuromuscular disorder that is characterized by progressive muscle wasting and weakness. It typically starts with muscle spasms and tremors in the arms, followed by muscle weakness and atrophy of muscles in the arms and legs. The facial and bulbar muscles are also involved. However, the muscle involvement pattern has not been investigated systemically in Kennedy disease.

The primary aim of the study is to investigate the muscle involvement in patients with Kennedy disease using MRI. Secondary aims are to examine disease severity and to test MRI as a potential outcome measure for future clinical trials in Kennedy disease.

Approximately 40 patients with Kennedy disease and 20 gender and age matched healthy voluntary controls will be recruited. The study consists of one visit per subject lasting 4-5 hours.

Conditions

  • Bulbo-Spinal Atrophy, X-Linked
  • Kennedy Disease

Interventions

OTHER

No intervention, observational

Sponsors & Collaborators

  • Rigshospitalet, Denmark

    lead OTHER

Principal Investigators

  • Julia R Dahlqvist, MD · Copenhagen Neuromuscular Center, Department of Neurology, Rigshospitalet, Copenhagen University

Eligibility

Min Age
18 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-09-30
Primary Completion
2017-02-28
Completion
2018-05-31

Countries

  • Denmark

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02501395 on ClinicalTrials.gov