Zoledronic Acid Combined Radiotherapy for Bone Metastasis of Non-small Cell Lung Cancer
NCT02480634 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 280
Last updated 2019-01-16
Summary
This study will give comparison of the bone pain remission and the adverse reaction of Zoledronic acid combine with High dose fractionation radiotherapy(30Gy/10f) and Zoledronic acid combine with low dose fractionation radiotherapy(15Gy/5f) . The purpose of this trial is to prove whether Zoledronic acid combine radiotherapy can reduce radiotherapy dose in treatment of non-small cell lung cancer bone metastasis'pain relief or not.
Conditions
- Non-small Cell Lung Cancer
- Bone Metastasis
Interventions
- DRUG
-
Zoledronic acid
Comparison the curative effect of the high does radiotherapy and low does therapy after use the Zoledronic acid
- RADIATION
-
Radiotherapy
High dose:30Gy/10f Low dose:15Gy/5f
Sponsors & Collaborators
-
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
lead OTHER
Principal Investigators
-
Ge Wang, Doctor · Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-06-30
- Primary Completion
- 2021-09-30
- Completion
- 2022-12-31
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