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A Bronchoscopy Study to Assess the Effects of Inhaled Corticosteroids on Adult Healthy Volunteers

NCT02476825 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2026-03-02

No results posted yet for this study

Summary

This is a randomized, single-blind, controlled, single centre bronchoscopy study designed to assess the effects of fluticasone propionate on airway gene expression and cellularity in healthy adult controls without asthma.

Conditions

  • Healthy

Interventions

DRUG

Fluticasone propionate

Flixotide Accuhaler 500 micrograms b.i.d.

DEVICE

Accuhaler

Flixotide Accuhaler 500 micrograms b.i.d.

Sponsors & Collaborators

  • Genentech, Inc.

    collaborator INDUSTRY

  • University Hospitals, Leicester

    lead OTHER

Principal Investigators

  • Peter Bradding, DM · University of Leicester/University Hospitals of Leicester NHS Trust

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-01-20
Primary Completion
2026-10-31
Completion
2026-10-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02476825 on ClinicalTrials.gov