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Genetic, Environment and Its Interaction Analysis for Cardiovascular Autonomic Neuropathy

NCT02461342 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 2100

Last updated 2016-09-22

No results posted yet for this study

Summary

A large-scale, community-based, cross-sectional study was conducted to explore the extent to which genetic, environment and its interactions associated with cardiovascular autonomic neuropathy (CAN) in general Chinese population. A total of more than 2000 participants were recruited by using multiple stages sampling (first cluster sampling and then simply sampling). Data involved in variables of genetic, environment were collected. Every participants was complete DNA extracted and genotyped by using single nucleotide polymorphism (SNP). Cardiovascular autonomic functions were measured by using short-term heart rate variability (HRV) to evaluate the outcome of CAN. Genetic analysis were employed to evaluate genetic variants, environmental risk factors and its interactions for CAN.

Conditions

  • Cardiovascular Autonomic Neuropathy

Interventions

OTHER

not intervention

This is a cross-sectional study, no intervention was performed.

Sponsors & Collaborators

  • Huashan Hospital

    collaborator OTHER

  • Shanghai Tongji Hospital, Tongji University School of Medicine

    lead OTHER

Principal Investigators

  • Zihui Tang, M.D and Ph.D · Huashan Hospital

Eligibility

Min Age
30 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-01-31
Primary Completion
2016-06-30
Completion
2016-07-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02461342 on ClinicalTrials.gov