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Review of Human Herpes Viruses in Burns

NCT02452229 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 10267

Last updated 2015-05-22

No results posted yet for this study

Summary

Herpes simplex virus, cytomegalovirus and varicella zoster virus infection are purported to play a pivotal role in morbidity and mortality in burns. Thus far, there is no existing systematic review (Level of Evidence III or higher) describing the unique role as well as concurrent infections of these viruses in burns. The aim of this review is to point out the clinical differences between these human herpes virus subtypes, to outline established therapy approaches, and to provide evidence for virus related morbidity and mortality in burns.

Conditions

  • Human Herpes Virus
  • Herpes Simplex Virus
  • Varicella-zoster Virus
  • Chickenpox
  • Cytomegalovirus
  • Burns

Interventions

OTHER

Review of the Literature for Human Herpes Virus infections

Review of the Medline database (PubMed and Ovid interface) for human herpes virus infections in burns as well as Web of Science interface. PRIMSA (preferred reporting items for systematic reviews and meta-analyses) guidelines and checklist were used.

Sponsors & Collaborators

  • Shriners Hospitals for Children

    collaborator OTHER

  • The University of Texas Medical Branch, Galveston

    lead OTHER

Principal Investigators

  • David N Herndon, MD, FACS · Department of Surgery, University of Texas Medical Branch and Shriners Hospitals for Children, Galveston, Texas, USA

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-03-31
Primary Completion
2015-05-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02452229 on ClinicalTrials.gov