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Scintigraphic Comparison of Lung Deposition With Two Nebulizers During Invasive Mechanical Ventilation

NCT02450279 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2017-11-08

No results posted yet for this study

Summary

Many devices are available for nebulising drug solution during invasive mechanical ventilation. Vibrating-mesh nebulizers ensure the highest lung deposition output. A recent international survey on aerosol therapy during mechanical ventilation (Ehrmann et al. 2013) reported that jet nebulizers remained the mostly used.

The aim of this study is to compare lung deposition of a radiolabeled administered with both nebulizers during invasive mechanical ventilation by planar scintigraphy.

Conditions

  • Post-operative Neurosurgery

Interventions

DRUG

technetium-99m - Diethylenetriaminepentaacetic acid

DEVICE

Vibrating-mesh nebulizer

DEVICE

Jet Nebulizer

OTHER

Planar scintigraphy

OTHER

Preoperative spirometry

Sponsors & Collaborators

  • Cliniques universitaires Saint-Luc- Université Catholique de Louvain

    lead OTHER

Principal Investigators

  • Pierre-François Laterre · Head of Intensive Care Unit, Cliniques Universitaires Saint-Luc

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-03-31
Primary Completion
2017-11-07

Countries

  • Belgium

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02450279 on ClinicalTrials.gov