MedTrace Logo

Comparison of Lung Deposition With the Aeroneb Solo Adapter and a Standard Jet Nebulizer by SPECT-CT

NCT02298101 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 6

Last updated 2015-11-17

No results posted yet for this study

Summary

Aeroneb Solo Adapter is a vibrating-mesh nebulizer Aeroneb Solo combined to a spacer specifically designed for spontaneously breathing patients. This device has not been investigated in vivo yet.

It's known that using a spacer during nebulization improves aerosol delivery. We hypothetized that lung deposition could be highly increased with the Aeroneb Solo Adapter in comparison to a standard jet nebulizer.

Conditions

  • Healthy

Interventions

DRUG

Technetium-99m - Diethylenetriaminepentaacetic acid

Solution placed on the nebulizer reservoir

DEVICE

Aeroneb Solo Adapter

Nebulizer

DEVICE

Opti-Mist Plus Nebulizer

Standard jet nebulizer

OTHER

Planar scintigraphy

Imaging technique to investigate whole lung deposition

OTHER

Single photon emission computed tomography

Imaging technique to investigate regional pulmonary deposition

OTHER

Spirometry

FEV1, FVC assessment

Sponsors & Collaborators

  • Cliniques universitaires Saint-Luc- Université Catholique de Louvain

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-09-30
Primary Completion
2015-06-30

Countries

  • Belgium

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02298101 on ClinicalTrials.gov