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IUI Schedule in Cases of High Progesterone

NCT02447588 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 70

Last updated 2015-05-19

No results posted yet for this study

Summary

Intrauterine insemination (IUI) combined with ovarian stimulation protocols has become one of the first alternative treatment against infertility, although results in gestational terms are highly variable, ranging between 10% and 25%. The influence of progesterone levels in stimulated cycles of intrauterine insemination is an aspect little studied; however, this information may be useful when synchronizing the time of insemination with the implantation window, as it has been observed that patients with elevated levels of progesterone in the follicular phase exhibit a significant decrease in ongoing pregnancy rates, these results being possible due to premature ovulation which causes asynchrony between the embryo and the endometrium.

Taking into account these considerations, the aim of the investigators' study is to determine the effectiveness, in terms of ongoing pregnancy rates, to advance the intrauterine insemination with sperm donor (24 hours post-hCG) with respect to the standard schedule (36 hours post-hCG) according progesterone levels determined the day of hCG administration

Conditions

Interventions

OTHER

IAD at 36 hours

Intrauterine insemination with sperm donor at 36 hours post-hCG

OTHER

IAD at 24 hours

Intrauterine insemination with sperm donor at 24 hours post-hCG

Sponsors & Collaborators

  • Vida Recoletas Sevilla

    collaborator OTHER

  • IVI Vigo

    collaborator OTHER

  • IVI Madrid

    lead OTHER

Principal Investigators

  • Antonio Requena, PhD, MD · IVI Madrid

Study Design

Allocation
RANDOMIZED
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-07-31
Primary Completion
2016-07-31
Completion
2016-10-31

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Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02447588 on ClinicalTrials.gov