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Correlation Between ΔPP/HR and ΔSV During Fluid Challenge.

NCT02439242 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2015-05-08

No results posted yet for this study

Summary

In high perioperative risk patients, guidelines suggest intraoperative haemodynamic optimization by measurement of stroke volume (SV) to guide fluid resucitation.This strategy requires an invasive monitoring and learning. Some studies tried to find SV surrogates based on haemodynamic usual parameters. In an experimental hemorrhagic shock, SV was correlated to the pulse pressure (PP) / heart rate (HR) ratio.

The investigators hypothesized that SV variations (ΔSV) would be correlated to the PP/HR ratio variations (ΔPP / HR) during fluid challenge, and ΔPP / HR would be able to detect a ΔSV greater than 10%.

Conditions

  • Hypovolemia

Interventions

DRUG

fluid challenge of saline

250 ml of saline

Sponsors & Collaborators

  • University Hospital, Caen

    lead OTHER

Principal Investigators

  • Olivier REBET · CHU CAEN

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-06-30
Primary Completion
2015-11-30
Completion
2015-11-30

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02439242 on ClinicalTrials.gov