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CHildhood ASthma and Environment Research Study - CHASER Study

NCT02433275 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 2660

Last updated 2026-04-13

No results posted yet for this study

Summary

"CHildhood ASthma and Environment Research study - CHASER study" is an observational longitudinal study in outpatient clinic of Pediatric Allergology \& Pulmonology (PAP) of Respiratory Disease Research Center (RDRC) within the Institute of Biomedicine and Molecular Immunology (IBIM) of the National Research Council (CNR) of Palermo (RDRC-IBIM CNR), Italy.

The first phase - transversal study will identify determinants of pediatric asthma control

The second phase - longitudinal study, in patients with persistent asthma, will be focused on:

* predictors for asthma exacerbations and loss of control
* real life adherence to asthma therapy guidelines
* phenotypic characterization through the collection of saliva samples
* assessment of alterations and inflammatory changes in the nasal mucosa through nasal brushing
* evaluation of the presence of 8-isoprostane, nicotine, cotinine and bisphenol-A through urine analysis.

Chaser Project is expected to improve the knowledge of pediatric asthma in patients with different level of control, identifying predictors for asthma exacerbations and loss of control.

Conditions

Sponsors & Collaborators

  • Stefania La Grutta, MD

    lead OTHER

Eligibility

Min Age
5 Years
Max Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-09-30
Primary Completion
2020-02-29
Completion
2020-02-29

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02433275 on ClinicalTrials.gov