Stereotactic Ablative Radiotherapy for Oligometastatic Non-small Cell Lung Cancer
NCT02417662 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 140
Last updated 2026-05-06
Summary
The trial will assess the addition of stereotactic ablative radiotherapy (SABR) to standard anti-cancer therapy (SACT) in patients with oligometastatic non-small cell lung cancer. Patients will be randomised to receive either standard treatment alone (SACT) or standard treatment with conventional radiotherapy (RT) and SABR.
Conditions
Interventions
- RADIATION
-
Radical Radiotherapy (Conventional RT and SABR)
Radical radiotherapy (conventional or SABR) to primary and SABR to the metastases
- OTHER
-
Non-investigational SACT
There is no intervention in the control group, patients will receive SACT. The choice of SACT is determined by the treating clinician and will be supplied from hospital commercial stock, and prepared and administered according to institutional guidelines.
Sponsors & Collaborators
- collaborator OTHER
-
University College, London
lead OTHER
Principal Investigators
-
Fiona McDonald · Royal Marsden NHS Foundation Trust
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-08-19
- Primary Completion
- 2026-09-30
- Completion
- 2028-08-31
Countries
- United Kingdom
Study Locations
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