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Brain Connectivity Supporting Language Recovery in Aphasia

NCT02416856 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 74

Last updated 2018-05-14

No results posted yet for this study

Summary

The integrity of structural connectivity supporting cortical regions in the left brain hemisphere is hypothesized to enable treatment-induced naming recovery in persons with language difficulties after a stroke (aphasia). The investigators will map whole brain connectivity (i.e., the brain connectome) to investigate the role of cortical connectivity in impairment (Aim 1) and recovery (Aim 2) in patients with aphasia undergoing treatment. This information will be used to construct personalized markers of anomia treatment outcome (Aim 3), which may serve as a guide for speech-language pathologists and neurologists when facing patient management decisions.

Conditions

  • Aphasia
  • Stroke
  • Speech Disorders
  • Communications Disorders

Sponsors & Collaborators

  • National Institute on Deafness and Other Communication Disorders (NIDCD)

    collaborator NIH

  • University of South Carolina

    collaborator OTHER

  • Medical University of South Carolina

    lead OTHER

Principal Investigators

  • Leonardo F Bonilha, MD · Assistant Professor

Eligibility

Min Age
25 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-06-30
Primary Completion
2017-05-31
Completion
2017-05-31

Countries

  • United States

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02416856 on ClinicalTrials.gov