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Pressure-dependent Changes in Hematocrit and Plasma Volume During Anesthesia

NCT02412189 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2015-04-09

No results posted yet for this study

Summary

The arterial blood pressure affects the ratio between filtration and reabsorption of fluids in the circulating blood volume and thereby the hematocrit. During induction of anesthesia blood pressure, hemoglobin level and hematocrit decreases. The aim of the study is to evaluate weather a maintained blood pressure with norepinephrine during anesthesia induction reduces the decrease in hematocrit.

Conditions

  • Blood Pressure
  • Hematocrit Change
  • Anesthesia

Interventions

PROCEDURE

Maintained blood pressure

Norepinephrine therapy to maintain preanesthesia blood pressure

DRUG

Norepinephrine

Norepinephrine therapy to maintain preanesthesia blood pressure

Sponsors & Collaborators

  • Sahlgrenska University Hospital

    lead OTHER

Principal Investigators

  • Andreas Nygren, MD PHD · Sweden: Sahlgrenska University hospital

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-02-28
Primary Completion
2015-04-30
Completion
2015-05-31

Countries

  • Sweden

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02412189 on ClinicalTrials.gov